Altered Expression of Vitamin D Metabolism Genes and Circulating MicroRNAs in PBMCs of Patients with Type 1 Diabetes: Their Association with Vitamin D Status and Ongoing Islet Autoimmunity

Background: The immunomodulatory role of 1,25-Dihydroxy vitamin D3 (1,25(OH)2D3) is exerted through its interaction with the vitamin D receptor (VDR) present on pancreatic and immune cells. While a deficiency in vitamin D has been linked to Type 1 Diabetes Mellitus (T1DM), the exact molecular mechan...

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Detalles Bibliográficos
Autores principales: Al-Nakhle, Hakeemah, Mohsen, Ihsan, Elnaem, Bashir, Alharbi, Abdullah, Alnakhli, Ibtisam, Almoarfi, Shareefa, Fallatah, Jameela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609170/
https://www.ncbi.nlm.nih.gov/pubmed/37888206
http://dx.doi.org/10.3390/ncrna9050060

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