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The Effects of a Short-Term Combined Exercise Program on Liver Steatosis Indices and the Lipidemic and Glycemic Profile in NAFLD Individuals: A Pilot Study

Non-alcoholic fatty liver disease (NAFLD) is a very common liver disease associated with obesity, unhealthy diet, and lack of physical exercise. Short-term aerobic or resistance exercise has been shown to result in reduced liver fat in patients with NAFLD; however, the impact of the combination of t...

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Autores principales: Voudouris, Dimitrios, Horianopoulou, Maria, Apostolopoulou, Zoi, Chryssanthopoulos, Costas, Bardopoulou, Mari, Maridaki, Maria, Vassilakopoulos, Theodoros, Koutsilieris, Michael, Philippou, Anastassios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609218/
https://www.ncbi.nlm.nih.gov/pubmed/37887399
http://dx.doi.org/10.3390/metabo13101074
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author Voudouris, Dimitrios
Horianopoulou, Maria
Apostolopoulou, Zoi
Chryssanthopoulos, Costas
Bardopoulou, Mari
Maridaki, Maria
Vassilakopoulos, Theodoros
Koutsilieris, Michael
Philippou, Anastassios
author_facet Voudouris, Dimitrios
Horianopoulou, Maria
Apostolopoulou, Zoi
Chryssanthopoulos, Costas
Bardopoulou, Mari
Maridaki, Maria
Vassilakopoulos, Theodoros
Koutsilieris, Michael
Philippou, Anastassios
author_sort Voudouris, Dimitrios
collection PubMed
description Non-alcoholic fatty liver disease (NAFLD) is a very common liver disease associated with obesity, unhealthy diet, and lack of physical exercise. Short-term aerobic or resistance exercise has been shown to result in reduced liver fat in patients with NAFLD; however, the impact of the combination of these types of exercise has received less attention. This study investigated the effect of a short-term (7 days) concurrent exercise training program performed daily on liver steatosis indices, as well as the glycemic and lipidemic profile of overweight/obese sedentary volunteers. Twenty adult patients (age: 47.3 ± 12.3 yrs, body mass index: 32.4 ± 3.4 kg/m(2)) with NAFLD, detected by ultrasound and hematological indices, participated in the study. Pre- and post-exercise intervention assessment included body weight (BW), waist circumference (WC), hip/waist ratio (H/W), Homeostasis Model Assessment Insulin Resistance (HOMA-IR), blood lipids, and steatosis indices. Fatty Liver Index, Lipid Accumulation Index, WC, H/W, triglycerides, and total cholesterol were improved (p < 0.05) post-exercise, while no differences (p > 0.05) were observed in BW, HOMA-IR, HDL, LDL, Hepatic Steatosis Index, and Framingham Steatosis Index compared to pre-exercise values. It is concluded that a 7-day combined exercise program can have beneficial effects on hepatic steatosis and central adiposity indices, independently of weight loss, in patients with NAFLD.
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spelling pubmed-106092182023-10-28 The Effects of a Short-Term Combined Exercise Program on Liver Steatosis Indices and the Lipidemic and Glycemic Profile in NAFLD Individuals: A Pilot Study Voudouris, Dimitrios Horianopoulou, Maria Apostolopoulou, Zoi Chryssanthopoulos, Costas Bardopoulou, Mari Maridaki, Maria Vassilakopoulos, Theodoros Koutsilieris, Michael Philippou, Anastassios Metabolites Article Non-alcoholic fatty liver disease (NAFLD) is a very common liver disease associated with obesity, unhealthy diet, and lack of physical exercise. Short-term aerobic or resistance exercise has been shown to result in reduced liver fat in patients with NAFLD; however, the impact of the combination of these types of exercise has received less attention. This study investigated the effect of a short-term (7 days) concurrent exercise training program performed daily on liver steatosis indices, as well as the glycemic and lipidemic profile of overweight/obese sedentary volunteers. Twenty adult patients (age: 47.3 ± 12.3 yrs, body mass index: 32.4 ± 3.4 kg/m(2)) with NAFLD, detected by ultrasound and hematological indices, participated in the study. Pre- and post-exercise intervention assessment included body weight (BW), waist circumference (WC), hip/waist ratio (H/W), Homeostasis Model Assessment Insulin Resistance (HOMA-IR), blood lipids, and steatosis indices. Fatty Liver Index, Lipid Accumulation Index, WC, H/W, triglycerides, and total cholesterol were improved (p < 0.05) post-exercise, while no differences (p > 0.05) were observed in BW, HOMA-IR, HDL, LDL, Hepatic Steatosis Index, and Framingham Steatosis Index compared to pre-exercise values. It is concluded that a 7-day combined exercise program can have beneficial effects on hepatic steatosis and central adiposity indices, independently of weight loss, in patients with NAFLD. MDPI 2023-10-13 /pmc/articles/PMC10609218/ /pubmed/37887399 http://dx.doi.org/10.3390/metabo13101074 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Voudouris, Dimitrios
Horianopoulou, Maria
Apostolopoulou, Zoi
Chryssanthopoulos, Costas
Bardopoulou, Mari
Maridaki, Maria
Vassilakopoulos, Theodoros
Koutsilieris, Michael
Philippou, Anastassios
The Effects of a Short-Term Combined Exercise Program on Liver Steatosis Indices and the Lipidemic and Glycemic Profile in NAFLD Individuals: A Pilot Study
title The Effects of a Short-Term Combined Exercise Program on Liver Steatosis Indices and the Lipidemic and Glycemic Profile in NAFLD Individuals: A Pilot Study
title_full The Effects of a Short-Term Combined Exercise Program on Liver Steatosis Indices and the Lipidemic and Glycemic Profile in NAFLD Individuals: A Pilot Study
title_fullStr The Effects of a Short-Term Combined Exercise Program on Liver Steatosis Indices and the Lipidemic and Glycemic Profile in NAFLD Individuals: A Pilot Study
title_full_unstemmed The Effects of a Short-Term Combined Exercise Program on Liver Steatosis Indices and the Lipidemic and Glycemic Profile in NAFLD Individuals: A Pilot Study
title_short The Effects of a Short-Term Combined Exercise Program on Liver Steatosis Indices and the Lipidemic and Glycemic Profile in NAFLD Individuals: A Pilot Study
title_sort effects of a short-term combined exercise program on liver steatosis indices and the lipidemic and glycemic profile in nafld individuals: a pilot study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609218/
https://www.ncbi.nlm.nih.gov/pubmed/37887399
http://dx.doi.org/10.3390/metabo13101074
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