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Design and Application of Portable Centrifuge Inspired by a Hand-Powered Spinning Top

Traditional centrifuges, extensively employed in biology, chemistry, medicine, and other domains for tasks such as blood separation and pathogen extraction, have certain limitations. Their high cost, substantial size, and reliance on electricity restrict their range of application. Contemporary cent...

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Detalles Bibliográficos
Autores principales: Tang, Dongbao, Duan, Ziwei, Liu, Luxuan, Jia, Zhaoyuan, Lang, Lijun, Tan, Yuyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609382/
https://www.ncbi.nlm.nih.gov/pubmed/37893405
http://dx.doi.org/10.3390/mi14101968
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author Tang, Dongbao
Duan, Ziwei
Liu, Luxuan
Jia, Zhaoyuan
Lang, Lijun
Tan, Yuyu
author_facet Tang, Dongbao
Duan, Ziwei
Liu, Luxuan
Jia, Zhaoyuan
Lang, Lijun
Tan, Yuyu
author_sort Tang, Dongbao
collection PubMed
description Traditional centrifuges, extensively employed in biology, chemistry, medicine, and other domains for tasks such as blood separation and pathogen extraction, have certain limitations. Their high cost, substantial size, and reliance on electricity restrict their range of application. Contemporary centrifuges, inspired by everyday items like paper trays and egg beaters, boast characteristics such as ease of operation, independence from electricity, and portability. These features offer unique advantages in specific situations, such as electricity shortages, inadequate infrastructure, and challenging medical conditions. Consequently, we designed a hand-powered portable centrifuge driven by pulling a rope. Our experiments revealed significant performance factors, including load capacity, rope length, and frequency of rope pulling. The results demonstrated that the revolutions per minute (RPM) of a hand-powered portable centrifuge were directly proportional to the length of the rope and the frequency of pulling, up to a certain limit, while inversely proportional to the load. When used for separating and washing polystyrene microspheres, the portable centrifuge’s performance equaled that of traditional centrifuges. According to relevant calculations, this centrifuge could be capable of meeting the application of blood separation. Therefore, we believe this portable centrifuge will find meaningful applications in similar areas, particularly in resource-poor settings.
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spelling pubmed-106093822023-10-28 Design and Application of Portable Centrifuge Inspired by a Hand-Powered Spinning Top Tang, Dongbao Duan, Ziwei Liu, Luxuan Jia, Zhaoyuan Lang, Lijun Tan, Yuyu Micromachines (Basel) Article Traditional centrifuges, extensively employed in biology, chemistry, medicine, and other domains for tasks such as blood separation and pathogen extraction, have certain limitations. Their high cost, substantial size, and reliance on electricity restrict their range of application. Contemporary centrifuges, inspired by everyday items like paper trays and egg beaters, boast characteristics such as ease of operation, independence from electricity, and portability. These features offer unique advantages in specific situations, such as electricity shortages, inadequate infrastructure, and challenging medical conditions. Consequently, we designed a hand-powered portable centrifuge driven by pulling a rope. Our experiments revealed significant performance factors, including load capacity, rope length, and frequency of rope pulling. The results demonstrated that the revolutions per minute (RPM) of a hand-powered portable centrifuge were directly proportional to the length of the rope and the frequency of pulling, up to a certain limit, while inversely proportional to the load. When used for separating and washing polystyrene microspheres, the portable centrifuge’s performance equaled that of traditional centrifuges. According to relevant calculations, this centrifuge could be capable of meeting the application of blood separation. Therefore, we believe this portable centrifuge will find meaningful applications in similar areas, particularly in resource-poor settings. MDPI 2023-10-22 /pmc/articles/PMC10609382/ /pubmed/37893405 http://dx.doi.org/10.3390/mi14101968 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tang, Dongbao
Duan, Ziwei
Liu, Luxuan
Jia, Zhaoyuan
Lang, Lijun
Tan, Yuyu
Design and Application of Portable Centrifuge Inspired by a Hand-Powered Spinning Top
title Design and Application of Portable Centrifuge Inspired by a Hand-Powered Spinning Top
title_full Design and Application of Portable Centrifuge Inspired by a Hand-Powered Spinning Top
title_fullStr Design and Application of Portable Centrifuge Inspired by a Hand-Powered Spinning Top
title_full_unstemmed Design and Application of Portable Centrifuge Inspired by a Hand-Powered Spinning Top
title_short Design and Application of Portable Centrifuge Inspired by a Hand-Powered Spinning Top
title_sort design and application of portable centrifuge inspired by a hand-powered spinning top
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609382/
https://www.ncbi.nlm.nih.gov/pubmed/37893405
http://dx.doi.org/10.3390/mi14101968
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