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A Review on Five and Six-Membered Heterocyclic Compounds Targeting the Penicillin-Binding Protein 2 (PBP2A) of Methicillin-Resistant Staphylococcus aureus (MRSA)

Staphylococcus aureus is a common human pathogen. Methicillin-resistant Staphylococcus aureus (MRSA) infections pose significant and challenging therapeutic difficulties. MRSA often acquires the non-native gene PBP2a, which results in reduced susceptibility to β-lactam antibiotics, thus conferring r...

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Detalles Bibliográficos
Autores principales: Ambade, Shraddha S., Gupta, Vivek Kumar, Bhole, Ritesh P., Khedekar, Pramod B., Chikhale, Rupesh V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609489/
https://www.ncbi.nlm.nih.gov/pubmed/37894491
http://dx.doi.org/10.3390/molecules28207008