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Loss in the Antibacterial Ability of a PyrR Gene Regulating Pyrimidine Biosynthesis after Using CRISPR/Cas9-Mediated Knockout for Metabolic Engineering in Lactobacillus casei

Lactobacillus casei (L. casei) has four possible mechanisms: antimicrobial antagonism, competitional adhesion, immunoregulation, and the inhibition of bacterial toxins. To delineate the metabolic reactions of nucleotides from L. casei that are associated with mechanisms of inhibiting pathogens and i...

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Detalles Bibliográficos
Autores principales:	Chen, Shaojun, He, Xinmiao, Qin, Ziliang, Li, Gang, Wang, Wentao, Nai, Zida, Tian, Yaguang, Liu, Di, Jiang, Xinpeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609543/ https://www.ncbi.nlm.nih.gov/pubmed/37894029 http://dx.doi.org/10.3390/microorganisms11102371

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