Cargando…
Design, Synthesis, In Vitro Biological Evaluation and In Silico Molecular Docking Study of Benzimidazole-Based Oxazole Analogues: A Promising Acetylcholinesterase and Butyrylcholinesterase Inhibitors
Alzheimer’s disease (AD) is a degenerative neurological condition that severely affects the elderly and is clinically recognised by a decrease in cognition and memory. The treatment of this disease has drawn considerable attention and sparked increased interest among the researchers in this field as...
Autores principales: | Hussain, Rafaqat, Rahim, Fazal, Ullah, Hayat, Khan, Shoaib, Sarfraz, Maliha, Iqbal, Rashid, Suleman, Faiza, Al-Sadoon, Mohammad Khalid |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609608/ https://www.ncbi.nlm.nih.gov/pubmed/37894494 http://dx.doi.org/10.3390/molecules28207015 |
Ejemplares similares
-
Multipotent Cholinesterase Inhibitors for the Treatment of Alzheimer’s Disease: Synthesis, Biological Analysis and Molecular Docking Study of Benzimidazole-Based Thiazole Derivatives
por: Hussain, Rafaqat, et al.
Publicado: (2022) -
Benzimidazole Bearing Thiosemicarbazone Derivatives Act as Potent α-Amylase and α-Glucosidase Inhibitors; Synthesis, Bioactivity Screening and Molecular Docking Study
por: Ullah, Hayat, et al.
Publicado: (2022) -
Synthesis, DFT Studies, Molecular Docking and Biological Activity Evaluation of Thiazole-Sulfonamide Derivatives as Potent Alzheimer’s Inhibitors
por: Khan, Shoaib, et al.
Publicado: (2023) -
Synthesis, in vitro biological assessment, and molecular docking study of benzimidazole-based thiadiazole derivatives as dual inhibitors of α-amylase and α-glucosidase
por: Khan, Shoaib, et al.
Publicado: (2023) -
Caffeine Inhibits Acetylcholinesterase, But Not Butyrylcholinesterase
por: Pohanka, Miroslav, et al.
Publicado: (2013)