Cargando…

Development of an HPLC-MS/MS Method for Chiral Separation and Quantitation of (R)- and (S)-Salbutamol and Their Sulfoconjugated Metabolites in Urine to Investigate Stereoselective Sulfonation

The aim of this study was to develop and optimize a chiral HPLC-MS/MS method for quantitative analysis of (R)-/(S)-salbutamol and (R)-/(S)-salbutamol-4′-O-sulfate in human urine to allow for bioanalytical quantitation of the targeted analytes and investigations of stereoselectivity in the sulfonatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Harps, Lukas Corbinian, Jendretzki, Annika Lisa, Wolf, Clemens Alexander, Girreser, Ulrich, Wolber, Gerhard, Parr, Maria Kristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609612/ https://www.ncbi.nlm.nih.gov/pubmed/37894685 http://dx.doi.org/10.3390/molecules28207206

Ejemplares similares

Enantioseparation and Determination of Penconazole in Rat Plasma by Chiral LC-MS/MS: Application to a Stereoselective Toxicokinetic Study
por: Ma, Siman, et al.
Publicado: (2020)

Development of an HPLC-MS/MS Method for the Determination of Silybin in Human Plasma, Urine and Breast Tissue
por: Lazzeroni, Matteo, et al.
Publicado: (2020)

Human Sulfotransferase Assays With PAPS Production in situ
por: Sun, Yanan, et al.
Publicado: (2022)

Atropisomeric determination of chiral hydroxylated metabolites of polychlorinated biphenyls using HPLC-MS
por: Zhai, Guangshu, et al.
Publicado: (2013)

Stereoselective pharmacokinetic study of epiprogoitrin and progoitrin in rats with UHPLC–MS/MS method
por: Xu, Yan, et al.
Publicado: (2020)

Determination of Oseltamivir in Human Plasma by HPLC-MS/MS
por: Lakeev, A. P., et al.
Publicado: (2023)

Validated HPLC-MS/MS Method To Quantify Low Levels of Domoic Acid in Plasma and Urine after Subacute Exposure
por: Shum, Sara, et al.
Publicado: (2018)

Phase II Metabolism of Asarone Isomers In Vitro and in Humans Using HPLC-MS/MS and HPLC-qToF/MS
por: Hermes, Lena, et al.
Publicado: (2021)

Magnetic Solid-Phase Extraction Based on Magnetic Sulfonated Reduced Graphene Oxide for HPLC–MS/MS Analysis of Illegal Basic Dyes in Foods
por: Cui, Shibo, et al.
Publicado: (2021)

Selective extraction and determination of aromatic amine metabolites in urine samples by using magnetic covalent framework nanocomposites and HPLC-MS/MS
por: Yu, Jingjing, et al.
Publicado: (2020)

HPLC-ESI-MS/MS of Imidazole Alkaloids in Pilocarpus microphyllus
por: Sawaya, Alexandra CH F, et al.
Publicado: (2008)

Development of an HPLC-MS/MS Method for the Determination of Alkaloids in Lupins
por: Eugelio, Fabiola, et al.
Publicado: (2023)

Speciation Analysis of Arsenic Compounds by HPLC-ICP-MS: Application for Human Serum and Urine
por: Nguyen, Manh Ha, et al.
Publicado: (2018)

Enantioseparation and Absolute Configuration Determination of Angular-Type Pyranocoumarins from Peucedani Radix Using Enzymatic Hydrolysis and Chiral HPLC-MS/MS Analysis
por: Song, Yue-Lin, et al.
Publicado: (2012)

Green Extraction of Alkaloids and Polyphenols from Peumus boldus Leaves with Natural Deep Eutectic Solvents and Profiling by HPLC-PDA-IT-MS/MS and HPLC-QTOF-MS/MS
por: Torres-Vega, Jeniffer, et al.
Publicado: (2020)

Comprehensive Quality Assessment of Kaixin Powder by HPLC–DAD Quantification and HPLC–QTOF-MS/MS Confirmation
por: Wang, Binbin, et al.
Publicado: (2021)

Simultaneous quantification of ginsenoside Rg1 and its metabolites by HPLC–MS/MS: Rg1 excretion in rat bile, urine and feces
por: He, Chiyu, et al.
Publicado: (2016)

Development and Validation of an HPLC-MS/MS Method for the Early Diagnosis of Aspergillosis
por: Cerqueira, Letícia B., et al.
Publicado: (2014)

HPLC-MS/MS Method for the Measurement of Insecticide Degradates in Baby Food
por: Radford, Samantha A., et al.
Publicado: (2014)

Determination of Glyphosate in White and Brown Rice with HPLC-ICP-MS/MS
por: Fontanella, Maria Chiara, et al.
Publicado: (2022)

Analysis of 3‐nitropropionic acid in Fabaceae plants by HPLC‐MS/MS
por: Takács, Orsolya, et al.
Publicado: (2022)

Extraction, Separation, and Identification of Phenolic Compounds in Virgin Olive Oil by HPLC-DAD and HPLC-MS
por: Tasioula-Margari, Maria, et al.
Publicado: (2015)

A validated HPLC-MS/MS method for simultaneously analyzing curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetra-hydrocurcumin and piperine in human plasma, urine or feces
por: Kroon, M.A.G.M., et al.
Publicado: (2023)

Dissipation Dynamics and Residue of Four Herbicides in Paddy Fields Using HPLC-MS/MS and GC-MS
por: Yu, Qian, et al.
Publicado: (2019)

Futility of current urine salbutamol doping control
por: Heuberger, Jules A. A. C., et al.
Publicado: (2018)

Cleaning up the masses: Exclusion lists to reduce contamination with HPLC-MS/MS()
por: Hodge, Kelly, et al.
Publicado: (2013)

Development and validation of an HPLC–MS/MS method to determine clopidogrel in human plasma
por: Liu, Gangyi, et al.
Publicado: (2016)

Analysis of Tetracyclines in Medicated Feed for Food Animal Production by HPLC-MS/MS
por: Gavilán, Rosa Elvira, et al.
Publicado: (2015)

Diagnostic accuracy of thromboelastometry and its correlation with the HPLC-MS/MS quantification test
por: de Aranda, V.F., et al.
Publicado: (2019)

Identification of unusual phospholipids from bovine heart mitochondria by HPLC-MS/MS
por: Kim, Junhwan, et al.
Publicado: (2020)

Identification and quantification of the bioactive components in Osmanthus fragrans roots by HPLC-MS/MS
por: Liao, Xiaoyan, et al.
Publicado: (2021)

The Determination of Polymyxin B in Critically Ill Patients by the HPLC-MS/MS Method
por: Wang, Yirong, et al.
Publicado: (2023)

Determination of Phosphoethanolamine in Urine with HPLC-ICPMS/MS Using 1,2-Hexanediol as a Chromatographic Eluent
por: Lajin, Bassam, et al.
Publicado: (2023)

Chemical Profiles and Simultaneous Quantification of Aurantii fructus by Use of HPLC-Q-TOF-MS Combined with GC-MS and HPLC Methods
por: He, Yingjie, et al.
Publicado: (2018)

Identification and Analysis of Amygdalin, Neoamygdalin and Amygdalin Amide in Different Processed Bitter Almonds by HPLC-ESI-MS/MS and HPLC-DAD
por: Xu, Shuya, et al.
Publicado: (2017)

Determination of fenticonazole in human plasma by HPLC–MS/MS and its application to pharmacokinetic studies()
por: Mao, Weixing, et al.
Publicado: (2017)

Determination of Puquitinib in Human Plasma by HPLC–ESI MS/MS: Application to Pharmacokinetic Study
por: Zhan, Jing, et al.
Publicado: (2018)

Development of an HPLC–MS/MS method for the determination of ceftolozane/tazobactam in bronchoalveolar lavage fluid
por: Sutherland, Christina A, et al.
Publicado: (2018)

Determination of Florfenicol, Thiamfenicol and Chloramfenicol at Trace Levels in Animal Feed by HPLC–MS/MS
por: Gavilán, Rosa Elvira, et al.
Publicado: (2019)

Rapid Characterization of Triterpene Saponins from Zornia brasiliensis by HPLC-ESI-MS/MS
por: Nascimento, Yuri Mangueira, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_frnhug0h8k32pan0abm19egk39