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Efficacy of the Multi-Target Compound E153 in Relieving Pain and Pruritus of Different Origins

Itch and pain are closely related but distinct sensations that share largely overlapping mediators and receptors. We hypothesized that the novel, multi-target compound E153 has the potential to attenuate pain and pruritus of different origins. After the evaluation of sigma receptor affinity and phar...

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Detalles Bibliográficos
Autores principales: Mogilski, Szczepan, Kubacka, Monika, Świerczek, Artur, Wyska, Elżbieta, Szczepańska, Katarzyna, Sapa, Jacek, Kieć-Kononowicz, Katarzyna, Łażewska, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10609854/
https://www.ncbi.nlm.nih.gov/pubmed/37895952
http://dx.doi.org/10.3390/ph16101481