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The Path from Nasal Tissue to Nasal Mucosa on Chip: Part 2—Advanced Microfluidic Nasal In Vitro Model for Drug Absorption Testing
The nasal mucosa, being accessible and highly vascularized, opens up new opportunities for the systemic administration of drugs. However, there are several protective functions like the mucociliary clearance, a physiological barrier which represents is a difficult obstacle for drug candidates to ove...
Autores principales: | Koch, Eugen Viktor, Bendas, Sebastian, Nehlsen, Kristina, May, Tobias, Reichl, Stephan, Dietzel, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610000/ https://www.ncbi.nlm.nih.gov/pubmed/37896199 http://dx.doi.org/10.3390/pharmaceutics15102439 |
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