Cargando…
Chimeric Peptide Engineered Nanomedicine for Synergistic Suppression of Tumor Growth and Therapy-Induced Hyperlipidemia by mTOR and PCSK9 Inhibition
Chemotherapy-induced side effects restrain anti-tumor efficiency, with hyperlipidemia being the most common accompanying disease to cause treatment failure. In this work, a chimeric peptide-engineered nanomedicine (designated as PRS) was fabricated for the synergistic suppression of tumor growth and...
Autores principales: | Cai, Hua, Zheng, Rongrong, Wu, Ningxia, Hu, Jiaman, Wang, Ruixin, Chi, Jianing, Zhang, Wei, Zhao, Linping, Cheng, Hong, Chen, Ali, Li, Shiying, Xu, Lin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610039/ https://www.ncbi.nlm.nih.gov/pubmed/37896137 http://dx.doi.org/10.3390/pharmaceutics15102377 |
Ejemplares similares
-
PCSK9 inhibition in the management of hyperlipidemia: focus on evolocumab
por: Blom, Dirk J, et al.
Publicado: (2016) -
Circulating levels of DDIT4 and mTOR, and contributions of BMI, inflammation and insulin sensitivity in hyperlipidemia
por: Pan, Xinyan, et al.
Publicado: (2022) -
Efficacy and Safety of the PCSK9 Inhibitor Evolocumab in Patients with Mixed Hyperlipidemia
por: Rosenson, Robert S., et al.
Publicado: (2016) -
Cyclopamine and Rapamycin Synergistically Inhibit mTOR Signalling in Mouse Hepatocytes, Revealing an Interaction of Hedgehog and mTor Signalling in the Liver
por: Spormann, Luise, et al.
Publicado: (2020) -
The prognostic nutritional index predicts all-cause mortality in critically ill patients with acute myocardial infarction
por: Huang, Yuekang, et al.
Publicado: (2023)