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Identification of Potential JNK3 Inhibitors: A Combined Approach Using Molecular Docking and Deep Learning-Based Virtual Screening
JNK3, a member of the MAPK family, plays a pivotal role in mediating cellular responses to stress signals, with its activation implicated in a myriad of inflammatory conditions. While JNK3 holds promise as a therapeutic target for neurodegenerative disorders such as Huntington’s, Parkinson’s, and Al...
Autores principales: | Yao, Chenpeng, Shen, Zheyuan, Shen, Liteng, Kadier, Kailibinuer, Zhao, Jingyi, Guo, Yu, Xu, Lei, Cao, Ji, Dong, Xiaowu, Yang, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610115/ https://www.ncbi.nlm.nih.gov/pubmed/37895928 http://dx.doi.org/10.3390/ph16101459 |
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