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Identification of Potential JNK3 Inhibitors: A Combined Approach Using Molecular Docking and Deep Learning-Based Virtual Screening

JNK3, a member of the MAPK family, plays a pivotal role in mediating cellular responses to stress signals, with its activation implicated in a myriad of inflammatory conditions. While JNK3 holds promise as a therapeutic target for neurodegenerative disorders such as Huntington’s, Parkinson’s, and Al...

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Detalles Bibliográficos
Autores principales: Yao, Chenpeng, Shen, Zheyuan, Shen, Liteng, Kadier, Kailibinuer, Zhao, Jingyi, Guo, Yu, Xu, Lei, Cao, Ji, Dong, Xiaowu, Yang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610115/
https://www.ncbi.nlm.nih.gov/pubmed/37895928
http://dx.doi.org/10.3390/ph16101459

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