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Development of Osthole-Loaded Microemulsions as a Prospective Ocular Delivery System for the Treatment of Corneal Neovascularization: In Vitro and In Vivo Assessments

Osthole (OST), a natural coumarin compound, has shown a significant inhibitory effect on corneal neovascularization (CNV). But, its effect on treating CNV is restricted by its water insolubility. To overcome this limitation, an OST-loaded microemulsion (OST-ME) was created to improve the drug’s ther...

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Detalles Bibliográficos
Autores principales: Zhang, Yali, Yang, Jingjing, Ji, Yinjian, Liang, Zhen, Wang, Yuwei, Zhang, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610237/
https://www.ncbi.nlm.nih.gov/pubmed/37895813
http://dx.doi.org/10.3390/ph16101342