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Development of Osthole-Loaded Microemulsions as a Prospective Ocular Delivery System for the Treatment of Corneal Neovascularization: In Vitro and In Vivo Assessments
Osthole (OST), a natural coumarin compound, has shown a significant inhibitory effect on corneal neovascularization (CNV). But, its effect on treating CNV is restricted by its water insolubility. To overcome this limitation, an OST-loaded microemulsion (OST-ME) was created to improve the drug’s ther...
Autores principales: | Zhang, Yali, Yang, Jingjing, Ji, Yinjian, Liang, Zhen, Wang, Yuwei, Zhang, Junjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610237/ https://www.ncbi.nlm.nih.gov/pubmed/37895813 http://dx.doi.org/10.3390/ph16101342 |
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