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Human β-Defensin 23 as a Carrier for In Vitro and In Vivo Delivery of mRNA

The successful application of mRNA therapeutics hinges on the effective intracellular delivery of mRNA both in vitro and in vivo. However, this remains a formidable challenge due to the polyanionic nature, longitudinal shape, and low nuclease resistance of mRNA. In this study, we introduce a novel m...

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Detalles Bibliográficos
Autores principales: Kim, Kyoung-Ran, Kim, Junghyun, Cho, Seunghye, Ahn, Dae-Ro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610245/
https://www.ncbi.nlm.nih.gov/pubmed/37896237
http://dx.doi.org/10.3390/pharmaceutics15102477