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Applications of Degradable Hydrogels in Novel Approaches to Disease Treatment and New Modes of Drug Delivery

Hydrogels are particularly suitable materials for loading drug delivery agents; their high water content provides a biocompatible environment for most biomolecules, and their cross-linked nature protects the loaded agents from damage. During delivery, the delivered substance usually needs to be rele...

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Detalles Bibliográficos
Autores principales: Hu, Bo, Gao, Jinyuan, Lu, Yu, Wang, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610366/
https://www.ncbi.nlm.nih.gov/pubmed/37896132
http://dx.doi.org/10.3390/pharmaceutics15102370
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author Hu, Bo
Gao, Jinyuan
Lu, Yu
Wang, Yuji
author_facet Hu, Bo
Gao, Jinyuan
Lu, Yu
Wang, Yuji
author_sort Hu, Bo
collection PubMed
description Hydrogels are particularly suitable materials for loading drug delivery agents; their high water content provides a biocompatible environment for most biomolecules, and their cross-linked nature protects the loaded agents from damage. During delivery, the delivered substance usually needs to be released gradually over time, which can be achieved by degradable cross-linked chains. In recent years, biodegradable hydrogels have become a promising technology in new methods of disease treatment and drug delivery methods due to their many advantageous properties. This review briefly discusses the degradation mechanisms of different types of biodegradable hydrogel systems and introduces the specific applications of degradable hydrogels in several new methods of disease treatment and drug delivery methods.
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spelling pubmed-106103662023-10-28 Applications of Degradable Hydrogels in Novel Approaches to Disease Treatment and New Modes of Drug Delivery Hu, Bo Gao, Jinyuan Lu, Yu Wang, Yuji Pharmaceutics Review Hydrogels are particularly suitable materials for loading drug delivery agents; their high water content provides a biocompatible environment for most biomolecules, and their cross-linked nature protects the loaded agents from damage. During delivery, the delivered substance usually needs to be released gradually over time, which can be achieved by degradable cross-linked chains. In recent years, biodegradable hydrogels have become a promising technology in new methods of disease treatment and drug delivery methods due to their many advantageous properties. This review briefly discusses the degradation mechanisms of different types of biodegradable hydrogel systems and introduces the specific applications of degradable hydrogels in several new methods of disease treatment and drug delivery methods. MDPI 2023-09-22 /pmc/articles/PMC10610366/ /pubmed/37896132 http://dx.doi.org/10.3390/pharmaceutics15102370 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Hu, Bo
Gao, Jinyuan
Lu, Yu
Wang, Yuji
Applications of Degradable Hydrogels in Novel Approaches to Disease Treatment and New Modes of Drug Delivery
title Applications of Degradable Hydrogels in Novel Approaches to Disease Treatment and New Modes of Drug Delivery
title_full Applications of Degradable Hydrogels in Novel Approaches to Disease Treatment and New Modes of Drug Delivery
title_fullStr Applications of Degradable Hydrogels in Novel Approaches to Disease Treatment and New Modes of Drug Delivery
title_full_unstemmed Applications of Degradable Hydrogels in Novel Approaches to Disease Treatment and New Modes of Drug Delivery
title_short Applications of Degradable Hydrogels in Novel Approaches to Disease Treatment and New Modes of Drug Delivery
title_sort applications of degradable hydrogels in novel approaches to disease treatment and new modes of drug delivery
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610366/
https://www.ncbi.nlm.nih.gov/pubmed/37896132
http://dx.doi.org/10.3390/pharmaceutics15102370
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