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Applications of Degradable Hydrogels in Novel Approaches to Disease Treatment and New Modes of Drug Delivery
Hydrogels are particularly suitable materials for loading drug delivery agents; their high water content provides a biocompatible environment for most biomolecules, and their cross-linked nature protects the loaded agents from damage. During delivery, the delivered substance usually needs to be rele...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610366/ https://www.ncbi.nlm.nih.gov/pubmed/37896132 http://dx.doi.org/10.3390/pharmaceutics15102370 |
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author | Hu, Bo Gao, Jinyuan Lu, Yu Wang, Yuji |
author_facet | Hu, Bo Gao, Jinyuan Lu, Yu Wang, Yuji |
author_sort | Hu, Bo |
collection | PubMed |
description | Hydrogels are particularly suitable materials for loading drug delivery agents; their high water content provides a biocompatible environment for most biomolecules, and their cross-linked nature protects the loaded agents from damage. During delivery, the delivered substance usually needs to be released gradually over time, which can be achieved by degradable cross-linked chains. In recent years, biodegradable hydrogels have become a promising technology in new methods of disease treatment and drug delivery methods due to their many advantageous properties. This review briefly discusses the degradation mechanisms of different types of biodegradable hydrogel systems and introduces the specific applications of degradable hydrogels in several new methods of disease treatment and drug delivery methods. |
format | Online Article Text |
id | pubmed-10610366 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-106103662023-10-28 Applications of Degradable Hydrogels in Novel Approaches to Disease Treatment and New Modes of Drug Delivery Hu, Bo Gao, Jinyuan Lu, Yu Wang, Yuji Pharmaceutics Review Hydrogels are particularly suitable materials for loading drug delivery agents; their high water content provides a biocompatible environment for most biomolecules, and their cross-linked nature protects the loaded agents from damage. During delivery, the delivered substance usually needs to be released gradually over time, which can be achieved by degradable cross-linked chains. In recent years, biodegradable hydrogels have become a promising technology in new methods of disease treatment and drug delivery methods due to their many advantageous properties. This review briefly discusses the degradation mechanisms of different types of biodegradable hydrogel systems and introduces the specific applications of degradable hydrogels in several new methods of disease treatment and drug delivery methods. MDPI 2023-09-22 /pmc/articles/PMC10610366/ /pubmed/37896132 http://dx.doi.org/10.3390/pharmaceutics15102370 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Hu, Bo Gao, Jinyuan Lu, Yu Wang, Yuji Applications of Degradable Hydrogels in Novel Approaches to Disease Treatment and New Modes of Drug Delivery |
title | Applications of Degradable Hydrogels in Novel Approaches to Disease Treatment and New Modes of Drug Delivery |
title_full | Applications of Degradable Hydrogels in Novel Approaches to Disease Treatment and New Modes of Drug Delivery |
title_fullStr | Applications of Degradable Hydrogels in Novel Approaches to Disease Treatment and New Modes of Drug Delivery |
title_full_unstemmed | Applications of Degradable Hydrogels in Novel Approaches to Disease Treatment and New Modes of Drug Delivery |
title_short | Applications of Degradable Hydrogels in Novel Approaches to Disease Treatment and New Modes of Drug Delivery |
title_sort | applications of degradable hydrogels in novel approaches to disease treatment and new modes of drug delivery |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610366/ https://www.ncbi.nlm.nih.gov/pubmed/37896132 http://dx.doi.org/10.3390/pharmaceutics15102370 |
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