Cargando…

Methyl Canthin-6-one-2-carboxylate Restrains the Migration/Invasion Properties of Fibroblast-like Synoviocytes by Suppressing the Hippo/YAP Signaling Pathway

Rheumatoid arthritis (RA) is an inflammatory condition that causes severe cartilage degradation and synovial damage in the joints with multiple systemic implications. Previous studies have revealed that fibroblast-like synoviocytes (FLSs) play a pivotal role in the pathogenesis of RA. The appropriat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Zongying, Wang, Yunhan, Xu, Qiuyun, Zhou, Xiaorong, Ling, Yong, Zhang, Jie, Mao, Liming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610387/ https://www.ncbi.nlm.nih.gov/pubmed/37895911 http://dx.doi.org/10.3390/ph16101440

Ejemplares similares

Canthin-6-Ones: Potential Drugs for Chronic Inflammatory Diseases by Targeting Multiple Inflammatory Mediators
por: Zhang, Zongying, et al.
Publicado: (2023)

Resolvin D1 inhibits the proliferation of osteoarthritis fibroblast-like synoviocytes through the Hippo-YAP signaling pathway
por: Su, Siwei, et al.
Publicado: (2022)

High Expression of CDCA7 in the Prognosis of Glioma and Its Relationship with Ferroptosis and Immunity
por: Wang, Yunhan, et al.
Publicado: (2023)

Predicting Prognosis and Immunotherapy Response in Multiple Cancers Based on the Association of PANoptosis-Related Genes with Tumor Heterogeneity
por: Wang, Yunhan, et al.
Publicado: (2023)

Huberine, a New Canthin-6-One Alkaloid from the Bark of Picrolemma huberi
por: López, Carlos, et al.
Publicado: (2018)

αCGRP Affects BMSCs’ Migration and Osteogenesis via the Hippo-YAP Pathway
por: Wang, Bin, et al.
Publicado: (2019)

Fruitful Decades for Canthin-6-ones from 1952 to 2015: Biosynthesis, Chemistry, and Biological Activities
por: Dai, Jiangkun, et al.
Publicado: (2016)

YAP and the Hippo pathway in cholangiocarcinoma
por: Sugihara, Takaaki, et al.
Publicado: (2019)

Hippo-YAP/TAZ signaling in angiogenesis
por: Park, Jeong Ae, et al.
Publicado: (2018)

Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms
por: Dobrokhotov, Oleg, et al.
Publicado: (2018)

Cyclooxygenase-2 Facilitates Newcastle Disease Virus Proliferation and Is as a Target for Canthin-6-One Antiviral Activity
por: Wang, Chongyang, et al.
Publicado: (2020)

Hippo/YAP signaling pathway is involved in osteosarcoma chemoresistance
por: Wang, Dong-Yu, et al.
Publicado: (2016)

The Hippo pathway member YAP enhances human neural crest cell fate and migration
por: Hindley, Christopher J., et al.
Publicado: (2016)

Novel Canthin-6-one Derivatives: Design, Synthesis, and Their Antiproliferative Activities via Inducing Apoptosis, Deoxyribonucleic Acid Damage, and Ferroptosis
por: Ding, Jinfeng, et al.
Publicado: (2023)

MicroRNA-9 restrains the sharp increase and boost apoptosis of human acute myeloid leukemia cells by adjusting the Hippo/YAP signaling pathway
por: Wang, Guoqing, et al.
Publicado: (2021)

Regulation of type I interferon signature by VGLL3 in the fibroblast-like synoviocytes of rheumatoid arthritis patients via targeting the Hippo pathway
por: Du, Yu, et al.
Publicado: (2022)

The Crosstalk Between Hippo-YAP Pathway and Innate Immunity
por: Wang, Shuai, et al.
Publicado: (2020)

LncRNA THRIL is involved in the proliferation, migration, and invasion of rheumatoid fibroblast-like synoviocytes
por: Zou, Yaoyao, et al.
Publicado: (2021)

Clinical potential of the Hippo-YAP pathway in bladder cancer
por: Cheng, Xin, et al.
Publicado: (2022)

The Multiple Interactions of RUNX with the Hippo–YAP Pathway
por: Chuang, Linda Shyue Huey, et al.
Publicado: (2021)

Hippo-Yap/Taz signalling in zebrafish regeneration
por: Riley, Susanna E., et al.
Publicado: (2022)

Functional role of PPAR-γ on the proliferation and migration of fibroblast-like synoviocytes in rheumatoid arthritis
por: Li, Xiao-Feng, et al.
Publicado: (2017)

YAP/TAZ: Key Players for Rheumatoid Arthritis Severity by Driving Fibroblast Like Synoviocytes Phenotype and Fibro-Inflammatory Response
por: Caire, Robin, et al.
Publicado: (2021)

DAB2 suppresses gastric cancer migration by regulating the Wnt/β-catenin and Hippo-YAP signaling pathways
por: Wang, Hua, et al.
Publicado: (2020)

SEPT6 drives hepatocellular carcinoma cell proliferation, migration and invasion via the Hippo/YAP signaling pathway
por: Fan, Yuhui, et al.
Publicado: (2021)

Hippo Pathway-independent Restriction of TAZ and YAP by Angiomotin
por: Chan, Siew Wee, et al.
Publicado: (2011)

An emerging role for Hippo-YAP signaling in cardiovascular development
por: Zhou, Jiliang
Publicado: (2014)

Role of Hippo Pathway-YAP/TAZ Signaling in Angiogenesis
por: Boopathy, Gandhi T. K., et al.
Publicado: (2019)

Control of skeletal morphogenesis by the Hippo-YAP/TAZ pathway
por: Vanyai, Hannah K., et al.
Publicado: (2020)

The role of Hippo‐YAP signaling in squamous cell carcinomas
por: Maehama, Tomohiko, et al.
Publicado: (2020)

Hippo-Yap Pathway Orchestrates Neural Crest Ontogenesis
por: Zhao, Xiaolei, et al.
Publicado: (2021)

New Insights into Hippo/YAP Signaling in Fibrotic Diseases
por: Mia, Masum M., et al.
Publicado: (2022)

Emerging Role of YAP and the Hippo Pathway in Prostate Cancer
por: Koinis, Filippos, et al.
Publicado: (2022)

The Hippo/YAP signaling pathway: the driver of cancer metastasis
por: Zhou, Tianxing, et al.
Publicado: (2023)

Quantitative proteomics reveals the antifungal effect of canthin-6-one isolated from Ailanthus altissima against Fusarium oxysporum f. sp. cucumerinum in vitro
por: Li, Yongchun, et al.
Publicado: (2021)

Knockdown of ADAM10 inhibits migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis
por: Li, Dan, et al.
Publicado: (2022)

The Hippo-YAP pathway in various cardiovascular diseases: Focusing on the inflammatory response
por: Zheng, Ancheng, et al.
Publicado: (2022)

Total Synthesis of Bioactive Canthine Alkaloid Cordatanine Comprising in Situ Double Oxidative Aromatization of Tetrahydrocarbazole
por: Shelar, Santosh V., et al.
Publicado: (2017)

YAP–VGLL4 antagonism defines the major physiological function of the Hippo signaling effector YAP
por: Cai, Jing, et al.
Publicado: (2022)

Regulation of the Hippo/YAP axis by CXCR7 in the tumorigenesis of gastric cancer
por: Wang, Tianshi, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_i7aittccdg6tghtn28los7fvs3