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Subconjunctival Delivery of Sorafenib-Tosylate-Loaded Cubosomes for Facilitated Diabetic Retinopathy Treatment: Formulation Development, Evaluation, Pharmacokinetic and Pharmacodynamic (PKPD) Studies

Diabetic retinopathy (DR) is a microvascular complication associated with vascular endothelial growth factor (VEGF) overexpression. Therapeutic delivery to the retina is a challenging phenomenon due to ocular biological barriers. Sorafenib tosylate (ST) is a lipophilic drug with low molecular weight...

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Detalles Bibliográficos
Autores principales:	Madhusudhan, Sharadha, Gupta, Naresh Vishal, Rahamathulla, Mohamed, Chidambaram, Saravana Babu, Osmani, Riyaz Ali M., Ghazwani, Mohammed, Ahmed, Mohammed Muqtader, Farhana, Syeda Ayesha, Sarhan, Mohammed Y., Tousif, Ahmed Hediyal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610393/ https://www.ncbi.nlm.nih.gov/pubmed/37896180 http://dx.doi.org/10.3390/pharmaceutics15102419

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