Cargando…

Adsorption and Recognition Property of Tyrosine Molecularly Imprinted Polymer Prepared via Electron Beam Irradiation

To realize the selective separation of L-tyrosine (L-Tyr) and avoid the drawbacks of traditional thermal polymerization, electron beam irradiation polymerization was developed for the fabrication of L-Tyr molecularly imprinted polymers (MIPs). Firstly, L-Tyr MIPs were prepared with methacrylic acid...

Descripción completa

Detalles Bibliográficos
Autores principales: Miao, Pengpai, Sang, Yanan, Gao, Jie, Han, Xiaobing, Zhao, Yuan, Chen, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610430/
https://www.ncbi.nlm.nih.gov/pubmed/37896292
http://dx.doi.org/10.3390/polym15204048
_version_ 1785128253124509696
author Miao, Pengpai
Sang, Yanan
Gao, Jie
Han, Xiaobing
Zhao, Yuan
Chen, Tao
author_facet Miao, Pengpai
Sang, Yanan
Gao, Jie
Han, Xiaobing
Zhao, Yuan
Chen, Tao
author_sort Miao, Pengpai
collection PubMed
description To realize the selective separation of L-tyrosine (L-Tyr) and avoid the drawbacks of traditional thermal polymerization, electron beam irradiation polymerization was developed for the fabrication of L-Tyr molecularly imprinted polymers (MIPs). Firstly, L-Tyr MIPs were prepared with methacrylic acid and ethylene glycol dimethacrylate and without an initiator. Then, the influence of absorbed dosage and temperature on the adsorption capacity of L-Tyr, as well as the thermodynamic behavior, were investigated. The maximum adsorption capacity of 10.96 mg/g for MIPs was obtained with an irradiation dosage of 340 kGy under 15 °C, and the ΔH(0) and ΔS(0) of the adsorption process are −99.79 kJ/mol and −0.31 kJ/mol·K, respectively. In addition, the effect of adsorption time on adsorption performance was evaluated under different initial concentrations, and the kinetic behavior was fitted with four different models. Finally, the recognition property of the obtained MIPs was investigated with L-Tyr and two analogues. The obtained MIPs have an imprinting factor of 5.1 and relatively high selective coefficients of 3.9 and 3.5 against L-tryptophan and L-phenylalanine, respectively. This work not only provided an L-Tyr MIP with high adsorption capacity and selectivity but also provided an effective and clean method for the synthesis of MIPs.
format Online
Article
Text
id pubmed-10610430
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-106104302023-10-28 Adsorption and Recognition Property of Tyrosine Molecularly Imprinted Polymer Prepared via Electron Beam Irradiation Miao, Pengpai Sang, Yanan Gao, Jie Han, Xiaobing Zhao, Yuan Chen, Tao Polymers (Basel) Article To realize the selective separation of L-tyrosine (L-Tyr) and avoid the drawbacks of traditional thermal polymerization, electron beam irradiation polymerization was developed for the fabrication of L-Tyr molecularly imprinted polymers (MIPs). Firstly, L-Tyr MIPs were prepared with methacrylic acid and ethylene glycol dimethacrylate and without an initiator. Then, the influence of absorbed dosage and temperature on the adsorption capacity of L-Tyr, as well as the thermodynamic behavior, were investigated. The maximum adsorption capacity of 10.96 mg/g for MIPs was obtained with an irradiation dosage of 340 kGy under 15 °C, and the ΔH(0) and ΔS(0) of the adsorption process are −99.79 kJ/mol and −0.31 kJ/mol·K, respectively. In addition, the effect of adsorption time on adsorption performance was evaluated under different initial concentrations, and the kinetic behavior was fitted with four different models. Finally, the recognition property of the obtained MIPs was investigated with L-Tyr and two analogues. The obtained MIPs have an imprinting factor of 5.1 and relatively high selective coefficients of 3.9 and 3.5 against L-tryptophan and L-phenylalanine, respectively. This work not only provided an L-Tyr MIP with high adsorption capacity and selectivity but also provided an effective and clean method for the synthesis of MIPs. MDPI 2023-10-11 /pmc/articles/PMC10610430/ /pubmed/37896292 http://dx.doi.org/10.3390/polym15204048 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Miao, Pengpai
Sang, Yanan
Gao, Jie
Han, Xiaobing
Zhao, Yuan
Chen, Tao
Adsorption and Recognition Property of Tyrosine Molecularly Imprinted Polymer Prepared via Electron Beam Irradiation
title Adsorption and Recognition Property of Tyrosine Molecularly Imprinted Polymer Prepared via Electron Beam Irradiation
title_full Adsorption and Recognition Property of Tyrosine Molecularly Imprinted Polymer Prepared via Electron Beam Irradiation
title_fullStr Adsorption and Recognition Property of Tyrosine Molecularly Imprinted Polymer Prepared via Electron Beam Irradiation
title_full_unstemmed Adsorption and Recognition Property of Tyrosine Molecularly Imprinted Polymer Prepared via Electron Beam Irradiation
title_short Adsorption and Recognition Property of Tyrosine Molecularly Imprinted Polymer Prepared via Electron Beam Irradiation
title_sort adsorption and recognition property of tyrosine molecularly imprinted polymer prepared via electron beam irradiation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610430/
https://www.ncbi.nlm.nih.gov/pubmed/37896292
http://dx.doi.org/10.3390/polym15204048
work_keys_str_mv AT miaopengpai adsorptionandrecognitionpropertyoftyrosinemolecularlyimprintedpolymerpreparedviaelectronbeamirradiation
AT sangyanan adsorptionandrecognitionpropertyoftyrosinemolecularlyimprintedpolymerpreparedviaelectronbeamirradiation
AT gaojie adsorptionandrecognitionpropertyoftyrosinemolecularlyimprintedpolymerpreparedviaelectronbeamirradiation
AT hanxiaobing adsorptionandrecognitionpropertyoftyrosinemolecularlyimprintedpolymerpreparedviaelectronbeamirradiation
AT zhaoyuan adsorptionandrecognitionpropertyoftyrosinemolecularlyimprintedpolymerpreparedviaelectronbeamirradiation
AT chentao adsorptionandrecognitionpropertyoftyrosinemolecularlyimprintedpolymerpreparedviaelectronbeamirradiation