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The Neuroprotective Effects of Flavonoid Fisetin against Corticosterone-Induced Cell Death through Modulation of ERK, p38, and PI3K/Akt/FOXO3a-Dependent Pathways in PC12 Cells
The overactive hypothalamic–pituitary–adrenal (HPA) axis is believed to trigger the overproduction of corticosterone, leading to neurotoxicity in the brain. Fisetin is a flavonoid commonly found in fruits and vegetables. It has been suggested to possess various biological activities, including antio...
Autores principales: | Chang, Pei-Rong, Liou, Je-Wen, Chen, Pei-Yi, Gao, Wan-Yun, Wu, Chia-Ling, Wu, Ming-Jiuan, Yen, Jui-Hung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610442/ https://www.ncbi.nlm.nih.gov/pubmed/37896136 http://dx.doi.org/10.3390/pharmaceutics15102376 |
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