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The Impact of Inflammation on the In Vivo Activity of the Renal Transporters OAT1/3 in Pregnant Women Diagnosed with Acute Pyelonephritis

Inflammation can regulate hepatic drug metabolism enzymes and transporters. The impact of inflammation on renal drug transporters remains to be elucidated. We aimed to quantify the effect of inflammation (caused by acute pyelonephritis) on the in vivo activity of renal OAT1/3, using the probe drug f...

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Detalles Bibliográficos
Autores principales:	Benzi, Jhohann Richard de Lima, Melli, Patrícia Pereira dos Santos, Duarte, Geraldo, Unadkat, Jashvant D., Lanchote, Vera Lucia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610490/ https://www.ncbi.nlm.nih.gov/pubmed/37896187 http://dx.doi.org/10.3390/pharmaceutics15102427

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