Cargando…

Selenadiazole Inhibited Adenovirus-Induced Apoptosis through the Oxidative-Damage-Mediated Bcl-2/Stat 3/NF-κB Signaling Pathway

Human adenovirus type 7 (HAdV7) infection causes severe pneumonia, yet there are still no breakthroughs in treatment options for adenovirus, and the road to antiviral drug development faces major challenges. We attempted to find new drugs and we stumbled upon one: selenadiazole. Selenadiazole has be...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xia, Lai, Jia, Su, Jingyao, Zhang, Kelan, Li, Jiali, Li, Chuqing, Ning, Zhihui, Wang, Chenyang, Zhu, Bing, Li, Yinghua, Zhao, Mingqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610542/ https://www.ncbi.nlm.nih.gov/pubmed/37895944 http://dx.doi.org/10.3390/ph16101474

Ejemplares similares

Carambolaside W Inhibited H1N1 Influenza Virus-Induced Oxidative Stress through STAT-3/BCL-XL Signaling Pathway
por: Su, Jingyao, et al.
Publicado: (2023)

Selenium Nanoparticles Control H1N1 Virus by Inhibiting Inflammatory Response and Cell Apoptosis
por: Su, Jingyao, et al.
Publicado: (2023)

Changes of Host Immunity Mediated by IFN-γ(+) CD8(+) T Cells in Children with Adenovirus Pneumonia in Different Severity of Illness
por: Zheng, Ruilin, et al.
Publicado: (2021)

Selenium nanoparticles inhibited H1N1 influenza virus-induced apoptosis by ROS-mediated signaling pathways
por: Liu, Xia, et al.
Publicado: (2022)

New Multi-1,2,3-Selenadiazole Aromatic Derivatives
por: Al-Smadi, Mousa, et al.
Publicado: (2005)

Synthesis, Characterization and Antimicrobial Activity of New 1,2,3-Selenadiazoles
por: Al-Smadi, Mousa, et al.
Publicado: (2008)

STAT5 regulation of BCL10 parallels constitutive NFκB activation in lymphoid tumor cells
por: Nagy, Zsuzsanna S, et al.
Publicado: (2009)

Human Adenoviruses, Cholesterol Trafficking, and NF-κB Signaling
por: Cianciola, Nicholas L., et al.
Publicado: (2018)

Inhibition of H3N2 Influenza Virus Induced Apoptosis by Selenium Nanoparticles with Chitosan through ROS-Mediated Signaling Pathways
por: Xu, Tiantian, et al.
Publicado: (2023)

4-(5-Chlorothiophen-2-yl)-1,2,3-selenadiazole
por: Sugumar, Paramasivam, et al.
Publicado: (2012)

JAK–STAT signalling shapes the NF‐κB response in CLL towards venetoclax sensitivity or resistance via Bcl‐XL
por: Haselager, Marco V., et al.
Publicado: (2023)

NF-κB promotes leaky expression of adenovirus genes in a replication-incompetent adenovirus vector
por: Machitani, M., et al.
Publicado: (2016)

Naringenin Induces HepG2 Cell Apoptosis via ROS-Mediated JAK-2/STAT-3 Signaling Pathways
por: Zhang, Ming, et al.
Publicado: (2023)

5-(2-Nitro-1-phenylbutyl)-4-phenyl-1,2,3-selenadiazole
por: Sankari, S., et al.
Publicado: (2012)

I(2)/DMSO-catalyzed one-pot approach for the synthesis of 1,3,4-selenadiazoles
por: Bowroju, Suresh Kuarm, et al.
Publicado: (2021)

Chrysophanol inhibits proliferation and induces apoptosis through NF-κB/cyclin D1 and NF-κB/Bcl-2 signaling cascade in breast cancer cell lines
por: Ren, Li, et al.
Publicado: (2018)

The mechanism of colon tissue damage mediated by HIF-1α/NF-κB/STAT1 in high-altitude environment
por: Cheng, Junfei, et al.
Publicado: (2022)

Suppression of Oncolytic Adenovirus-Mediated Hepatotoxicity by Liver-Specific Inhibition of NF-κB
por: Machitani, Mitsuhiro, et al.
Publicado: (2017)

Scaffold compound L971 exhibits anti‐inflammatory activities through inhibition of JAK/STAT and NFκB signalling pathways
por: Li, Mengyuan, et al.
Publicado: (2021)

Regulatory T cells promote glioma cell stemness through TGF-β–NF-κB–IL6–STAT3 signaling
por: Liu, Shasha, et al.
Publicado: (2021)

Atypical IκB Bcl3 enhances the generation of the NF-κB p52 homodimer
por: Pan, Wenfei, et al.
Publicado: (2022)

STAT3/NF-κB decoy oligodeoxynucleotides inhibit atherosclerosis through regulation of the STAT/NF-κB signaling pathway in a mouse model of atherosclerosis
por: An, Hyun-Jin, et al.
Publicado: (2023)

Perfluorocarbon reduces cell damage from blast injury by inhibiting signal paths of NF-κB, MAPK and Bcl-2/Bax signaling pathway in A549 cells
por: Zhang, Zhaorui, et al.
Publicado: (2017)

LIGHT/IFN‐γ triggers β cells apoptosis via NF‐κB/Bcl2‐dependent mitochondrial pathway
por: Zheng, Quan‐You, et al.
Publicado: (2016)

The CARMA3-BCL10-MALT1 (CBM) complex contributes to DNA damage-induced NF-κB activation and cell survival
por: Zhang, Shilei, et al.
Publicado: (2017)

Regulatory Networks Involving STATs, IRFs, and NFκB in Inflammation
por: Platanitis, Ekaterini, et al.
Publicado: (2018)

5-[1-(4-Methylphenyl)-2-nitrobutyl]-4-phenyl-1,2,3-selenadiazole
por: Sugumar, P., et al.
Publicado: (2013)

IL‐25 promotes cisplatin resistance of lung cancer cells by activating NF‐κB signaling pathway to increase of major vault protein
por: Shen, Weiming, et al.
Publicado: (2019)

The effect of NF-κB antisense oligonucleotide on transdifferentiation of fibroblast in lung tissue of mice injured by bleomycin
por: Zhou, Yan, et al.
Publicado: (2014)

Apoptosis induced by β,β-dimethylacrylshikonin is associated with Bcl-2 and NF-κB in human breast carcinoma MCF-7 cells
por: XIONG, YAO, et al.
Publicado: (2013)

Disabled‐1 is down‐regulated in clinical breast cancer and regulates cell apoptosis through NF‐κB/Bcl‐2/caspase‐9
por: Cao, Rang‐Juan, et al.
Publicado: (2018)

Rsf-1 regulates malignant melanoma cell viability and chemoresistance via NF-κB/Bcl-2 signaling
por: He, Jiani, et al.
Publicado: (2019)

Inhibiting the NF-κB pathway enhances the antitumor effect of cabazitaxel by downregulating Bcl-2 in pancreatic cancer
por: Li, Zequn, et al.
Publicado: (2020)

STAT3 and NF-κB are Simultaneously Suppressed in Dendritic Cells in Lung Cancer
por: Li, Rui, et al.
Publicado: (2017)

miR-383 increases the cisplatin sensitivity of lung adenocarcinoma cells through inhibition of the RBM24-mediated NF-κB signaling pathway
por: He, Bo, et al.
Publicado: (2021)

Destruction of Neutrophil Extracellular Traps Promotes the Apoptosis and Inhibits the Invasion of Gastric Cancer Cells by Regulating the Expression of Bcl-2, Bax and NF-κB
por: Li, Rong, et al.
Publicado: (2020)

Methane-Rich Saline Counteracts Cholestasis-Induced Liver Damage via Regulating the TLR4/NF-κB/NLRP3 Inflammasome Pathway
por: Li, Zeyu, et al.
Publicado: (2019)

Reciprocal interplay between OTULIN–LUBAC determines genotoxic and inflammatory NF-κB signal responses
por: Li, Mingqi, et al.
Publicado: (2022)

5-[1-(4-Methoxyphenyl)-2-nitrobutyl]-4-phenyl-1,2,3-selenadiazole
por: Sugumar, P., et al.
Publicado: (2012)

Synthesis, antimicrobial and in vitro antitumor activities of a series of 1,2,3-thiadiazole and 1,2,3-selenadiazole derivatives
por: Mhaidat, Nizar M, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_tmk4c7i2u9bp5e9rhl2km76g07