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In Silico Analyses, Experimental Verification and Application in DNA Vaccines of Ebolavirus GP-Derived pan-MHC-II-Restricted Epitopes

(1) Background and Purpose: Ebola virus (EBOV) is the causative agent of Ebola virus disease (EVD), which causes extremely high mortality and widespread epidemics. The only glycoprotein (GP) on the surface of EBOV particles is the key to mediating viral invasion into host cells. DNA vaccines for EBO...

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Detalles Bibliográficos
Autores principales: Zhang, Junqi, Sun, Baozeng, Shen, Wenyang, Wang, Zhenjie, Liu, Yang, Sun, Yubo, Zhang, Jiaxing, Liu, Ruibo, Wang, Yongkai, Bai, Tianyuan, Ma, Zilu, Luo, Cheng, Qiao, Xupeng, Zhang, Xiyang, Yang, Shuya, Sun, Yuanjie, Jiang, Dongbo, Yang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10610722/
https://www.ncbi.nlm.nih.gov/pubmed/37897022
http://dx.doi.org/10.3390/vaccines11101620