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MDA5 with Complete CARD2 Region Inhibits the Early Replication of H9N2 AIV and Enhances the Immune Response during Vaccination

Chicken melanoma differentiation-associated gene 5 (MDA5) is a member of the RLRs family that recognizes the viral RNAs invading cells and activates downstream interferon regulatory pathways, thereby inhibiting viral replication. The caspase activation and recruitment domain (CARD) is the most impor...

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Detalles Bibliográficos
Autores principales:	Li, Tongtong, Cai, Yiqin, Li, Chenfei, Huang, Jingwen, Chen, Jiajing, Zhang, Ze, Cao, Ruibing, Zhou, Bin, Feng, Xiuli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611263/ https://www.ncbi.nlm.nih.gov/pubmed/37896944 http://dx.doi.org/10.3390/vaccines11101542

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