Multiple Hepatic Lipoma: A Case Report of Captive Hill Mynah with Iron Storage Disease

SIMPLE SUMMARY: The lipoma is a benign tumor consisting of mature adipocytes. Although lipomas can arise anywhere on the body, hepatic lipomas are rarely observed; thus, only a few hepatic lipoma cases are documented in veterinary medicine. According to previous research, the majority of hepatic lipomas are generally observed as solitary nodular structures. However, recently, multiple hepatic lipomas were found in a captive hill mynah. In the present case, the liver tissue from the bird exhibited not only multiple hepatic lipomas, but also excessive iron accumulation. To the best knowledge of the authors, this is the first report of multiple hepatic lipomas accompanying ISD, and herein, these unique pathological findings are reported. ABSTRACT: The present case describes multiple hepatic lipomas in a common hill mynah (Gracula religiosa). A 21-year-old female captive common hill mynah died without any notable clinical symptoms. An autopsy and histopathological examinations were conducted to determine the exact cause of death. On gross observation, the liver demonstrated a yellowish white surface color and multiple nodules indicating neoplastic lesions. Histopathological assessment found that the nodules purely comprised mature adipocytes. Furthermore, the liver exhibited an excessive accumulation of iron in hepatocytes and Kupffer cells and the infiltration of chronic inflammatory cells, suggesting iron storage disease (ISD). Based on the results, the present case was diagnosed as multiple hepatic lipomas with ISD. To the authors’ best knowledge, multiple hepatic lipomas accompanying ISD lesions have not been reported previously. Hence, the present case is the first case report of hepatic multiple lipomas with ISD in veterinary medicine.