A randomized, double-blind, placebo-controlled study of histone deacetylase type 6 inhibition for the treatment of painful diabetic peripheral neuropathy

INTRODUCTION: Current treatments for painful diabetic peripheral neuropathy (DPN) are insufficiently effective for many individuals and do not treat nonpain signs and symptoms. The enzyme histone deacetylase type 6 (HDAC6) may play a role in the pathophysiology of painful DPN, and inhibition of HDAC...

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Detalles Bibliográficos
Autores principales: Michelson, David, Chin, William W., Dworkin, Robert H., Freeman, Roy, Herrmann, David N., Mazitschek, Ralph, Pop-Busui, Rodica, Shaibani, Aziz, Vornov, James, Jones, Melissa, Jarpe, Matthew, Hader, Brittany, Viera, Theresa, Hylan, Michelle, Kachmar, Tim, Jones, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2023
Materias:
Neuropathic
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611336/
https://www.ncbi.nlm.nih.gov/pubmed/37899940
http://dx.doi.org/10.1097/PR9.0000000000001114

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