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Genome-Wide Profiling of Transcriptome and DNA Methylome in Human Embryonic Stem Cells Exposed to Extractable Organic Matter from PM2.5

Increasing evidence indicates that PM2.5 exposure disrupts early embryonic development, but the mechanisms remain unclear. We hypothesized that PM2.5 cause abnormal embryonic development by interfering with DNA methylation and mRNA expression. In this study, we observed that human embryonic stem cel...

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Detalles Bibliográficos
Autores principales: Wang, Jianming, Liu, Tiantian, Wang, Jin, Chen, Tao, Jiang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611369/
https://www.ncbi.nlm.nih.gov/pubmed/37888691
http://dx.doi.org/10.3390/toxics11100840