A Novel Rotavirus Reverse Genetics Platform Supports Flexible Insertion of Exogenous Genes and Enables Rapid Development of a High-Throughput Neutralization Assay

Despite the success of rotavirus vaccines, rotaviruses remain one of the leading causes of diarrheal diseases, resulting in significant childhood morbidity and mortality, especially in low- and middle-income countries. The reverse genetics system enables the manipulation of the rotavirus genome and...

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Detalles Bibliográficos
Autores principales: Wei, Jiajie, Radcliffe, Scott, Pirrone, Amanda, Lu, Meiqing, Li, Yuan, Cassaday, Jason, Newhard, William, Heidecker, Gwendolyn J., Rose II, William A., He, Xi, Freed, Daniel, Citron, Michael, Espeseth, Amy, Wang, Dai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611407/
https://www.ncbi.nlm.nih.gov/pubmed/37896813
http://dx.doi.org/10.3390/v15102034

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