Confirmation of canine acanthomatous ameloblastoma using RAS Q61R immunohistochemical staining of formalin-fixed paraffin-embedded tissues

Differentiating canine acanthomatous ameloblastoma (CAA) from oral squamous cell carcinoma (OSCC) based on routine histopathology can be challenging. We have previously shown that more than 95% of CAAs harbor an HRAS p.Q61R somatic mutation, while OSCCs carry either wild-type alleles or other MAPK p...

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Detalles Bibliográficos
Autores principales: Peralta, Santiago, Marcinczyk, Magdalena M., Katt, William P., Duhamel, Gerald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Veterinary Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611472/
https://www.ncbi.nlm.nih.gov/pubmed/37901104
http://dx.doi.org/10.3389/fvets.2023.1281022

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