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Inclisiran: a new generation of lipid-lowering siRNA therapeutic

Atherosclerotic heart disease (AHD) is a major cause of morbidity and mortality worldwide. Lowering low-density lipoprotein cholesterol (LDL-C) levels is a key strategy to prevent and treat AHD. Inclisiran is a novel siRNA drug that targets proprotein convertase subtilisin/kexin type 9 (PCSK9) gene...

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Detalles Bibliográficos
Autores principales:	Zhang, Yanzhen, Chen, Huaigang, Hong, Lang, Wang, Hong, Li, Bin, Zhang, Mengyin, Li, Jiamei, Yang, Liu, Liu, Fan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611522/ https://www.ncbi.nlm.nih.gov/pubmed/37900173 http://dx.doi.org/10.3389/fphar.2023.1260921

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