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Repeat Surgery for Vestibular Schwannomas: An Institutional Case Series

Introduction  Vestibular schwannomas (VSs) are treated with microsurgery and/or radiosurgery. Repeat resection is rare, and few studies have reported postoperative outcomes. The objective of this study was to describe clinical characteristics and outcomes in patients undergoing repeat surgery for VS...

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Autores principales: Nandoliya, Khizar R., Winterhalter, Emily J., Karras, Constantine L., Khazanchi, Rushmin, Youngblood, Mark W., Texakalidis, Pavlos, Chandler, James P., Magill, Stephen T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611534/
https://www.ncbi.nlm.nih.gov/pubmed/37900579
http://dx.doi.org/10.1055/s-0043-1776124
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author Nandoliya, Khizar R.
Winterhalter, Emily J.
Karras, Constantine L.
Khazanchi, Rushmin
Youngblood, Mark W.
Texakalidis, Pavlos
Chandler, James P.
Magill, Stephen T.
author_facet Nandoliya, Khizar R.
Winterhalter, Emily J.
Karras, Constantine L.
Khazanchi, Rushmin
Youngblood, Mark W.
Texakalidis, Pavlos
Chandler, James P.
Magill, Stephen T.
author_sort Nandoliya, Khizar R.
collection PubMed
description Introduction  Vestibular schwannomas (VSs) are treated with microsurgery and/or radiosurgery. Repeat resection is rare, and few studies have reported postoperative outcomes. The objective of this study was to describe clinical characteristics and outcomes in patients undergoing repeat surgery for VS. Methods  All adult (≥ 18 years) patients undergoing VS resection between 2003 and 2022 at our institution were retrospectively reviewed to identify patients who underwent repeat surgery of an ipsilateral VS following prior gross-total (GTR) or subtotal resection. Patient, radiographic, and clinical characteristics were reviewed. Primary outcomes were postoperative tumor volume, extent of resection, postoperative cranial nerve deficits, and time to further tumor progression. Results  Of 102 patients undergoing VS resection, 6 (5.9%) had undergone repeat surgery. Median (range) follow-up was 20 (5–117) months. Three patients were female. Median age was 56 (36–60) years. Median pre- and postoperative tumor volumes were 8.2 (1.8–28.2) cm (3) and 0.4 (0–3.8) cm (3) . GTR was achieved in two patients. Four patients had higher House-Brackmann scores at last follow-up, but none had tumor progression. Conclusion  In this small cohort of patients, repeat resection of recurrent or progressive VS can effectively reduce tumor volume with acceptable perioperative outcomes.
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spelling pubmed-106115342023-10-28 Repeat Surgery for Vestibular Schwannomas: An Institutional Case Series Nandoliya, Khizar R. Winterhalter, Emily J. Karras, Constantine L. Khazanchi, Rushmin Youngblood, Mark W. Texakalidis, Pavlos Chandler, James P. Magill, Stephen T. J Neurol Surg Rep Introduction  Vestibular schwannomas (VSs) are treated with microsurgery and/or radiosurgery. Repeat resection is rare, and few studies have reported postoperative outcomes. The objective of this study was to describe clinical characteristics and outcomes in patients undergoing repeat surgery for VS. Methods  All adult (≥ 18 years) patients undergoing VS resection between 2003 and 2022 at our institution were retrospectively reviewed to identify patients who underwent repeat surgery of an ipsilateral VS following prior gross-total (GTR) or subtotal resection. Patient, radiographic, and clinical characteristics were reviewed. Primary outcomes were postoperative tumor volume, extent of resection, postoperative cranial nerve deficits, and time to further tumor progression. Results  Of 102 patients undergoing VS resection, 6 (5.9%) had undergone repeat surgery. Median (range) follow-up was 20 (5–117) months. Three patients were female. Median age was 56 (36–60) years. Median pre- and postoperative tumor volumes were 8.2 (1.8–28.2) cm (3) and 0.4 (0–3.8) cm (3) . GTR was achieved in two patients. Four patients had higher House-Brackmann scores at last follow-up, but none had tumor progression. Conclusion  In this small cohort of patients, repeat resection of recurrent or progressive VS can effectively reduce tumor volume with acceptable perioperative outcomes. Georg Thieme Verlag KG 2023-10-27 /pmc/articles/PMC10611534/ /pubmed/37900579 http://dx.doi.org/10.1055/s-0043-1776124 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Nandoliya, Khizar R.
Winterhalter, Emily J.
Karras, Constantine L.
Khazanchi, Rushmin
Youngblood, Mark W.
Texakalidis, Pavlos
Chandler, James P.
Magill, Stephen T.
Repeat Surgery for Vestibular Schwannomas: An Institutional Case Series
title Repeat Surgery for Vestibular Schwannomas: An Institutional Case Series
title_full Repeat Surgery for Vestibular Schwannomas: An Institutional Case Series
title_fullStr Repeat Surgery for Vestibular Schwannomas: An Institutional Case Series
title_full_unstemmed Repeat Surgery for Vestibular Schwannomas: An Institutional Case Series
title_short Repeat Surgery for Vestibular Schwannomas: An Institutional Case Series
title_sort repeat surgery for vestibular schwannomas: an institutional case series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611534/
https://www.ncbi.nlm.nih.gov/pubmed/37900579
http://dx.doi.org/10.1055/s-0043-1776124
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