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Transglutaminase 2 Prevents Premature Senescence and Promotes Osteoblastic Differentiation of Mesenchymal Stem Cells through NRF2 Activation

Transglutaminase 2 (TG2) is a multifunctional enzyme that exhibits transamidase, GTPase, kinase, and protein disulfide isomerase (PDI) activities. Of these, transamidase-mediated modification of proteins regulates apoptosis, differentiation, inflammation, and fibrosis. TG2 is highly expressed in mes...

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Detalles Bibliográficos
Autores principales: Lee, Soo-Jin, Shin, Ji-Woong, Kwon, Mee-Ae, Lee, Ki Baek, Kim, Hyo-Jun, Lee, Jin-Haeng, Kang, Heun-Soo, Jun, Jong Kwan, Cho, Sung-Yup, Kim, In-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611545/
https://www.ncbi.nlm.nih.gov/pubmed/37900967
http://dx.doi.org/10.1155/2023/8815888

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