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Transglutaminase 2 Prevents Premature Senescence and Promotes Osteoblastic Differentiation of Mesenchymal Stem Cells through NRF2 Activation
Transglutaminase 2 (TG2) is a multifunctional enzyme that exhibits transamidase, GTPase, kinase, and protein disulfide isomerase (PDI) activities. Of these, transamidase-mediated modification of proteins regulates apoptosis, differentiation, inflammation, and fibrosis. TG2 is highly expressed in mes...
Autores principales: | Lee, Soo-Jin, Shin, Ji-Woong, Kwon, Mee-Ae, Lee, Ki Baek, Kim, Hyo-Jun, Lee, Jin-Haeng, Kang, Heun-Soo, Jun, Jong Kwan, Cho, Sung-Yup, Kim, In-Gyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611545/ https://www.ncbi.nlm.nih.gov/pubmed/37900967 http://dx.doi.org/10.1155/2023/8815888 |
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