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Molecular basis for ubiquitin/Fubi cross-reactivity in USP16 and USP36

Ubiquitin and ubiquitin-like proteins typically use distinct machineries to facilitate diverse functions. The immunosuppressive ubiquitin-like protein Fubi is synthesized as an N-terminal fusion to a ribosomal protein (Fubi-S30). Its proteolytic maturation by the nucleolar deubiquitinase USP36 is st...

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Detalles Bibliográficos
Autores principales: O’Dea, Rachel, Kazi, Nafizul, Hoffmann-Benito, Alicia, Zhao, Zhou, Recknagel, Sarah, Wendrich, Kim, Janning, Petra, Gersch, Malte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611586/
https://www.ncbi.nlm.nih.gov/pubmed/37443395
http://dx.doi.org/10.1038/s41589-023-01388-1

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