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Novel, clinically relevant genomic patterns identified by comprehensive genomic profiling in ATRX-deficient IDH-wildtype adult high-grade gliomas

Glioblastomas are the most common IDH-wildtype adult high-grade gliomas, frequently harboring mutations in the TERT gene promoter (pTERT) and utilizing the subsequent telomerase overexpression for telomere length maintenance. However, some rare cases show loss of ATRX and use alternative mechanisms...

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Detalles Bibliográficos
Autores principales:	Bedics, Gábor, Szőke, Péter, Bátai, Bence, Nagy, Tibor, Papp, Gergő, Kránitz, Noémi, Rajnai, Hajnalka, Reiniger, Lilla, Bödör, Csaba, Scheich, Bálint
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10611758/ https://www.ncbi.nlm.nih.gov/pubmed/37891325 http://dx.doi.org/10.1038/s41598-023-45786-w

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