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Immunogenicity and Tolerability of a SARS-CoV-2 TNX-1800, a Live Recombinant Poxvirus Vaccine Candidate, in Syrian Hamsters and New Zealand White Rabbits

TNX-1800 is a preclinical stage synthetic-derived live attenuated chimeric horsepox virus vaccine engineered to express the SARS-CoV-2 spike (S) gene. The objectives of this study were to assess the safety, tolerability, and immunogenicity of TNX-1800 administration in Syrian golden hamsters and New...

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Detalles Bibliográficos
Autores principales: Awasthi, Mayanka, Macaluso, Anthony, Goebel, Scott J., Luea, Erin, Noyce, Ryan S., Nasar, Farooq, Daugherty, Bruce, Bavari, Sina, Lederman, Seth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612059/
https://www.ncbi.nlm.nih.gov/pubmed/37896908
http://dx.doi.org/10.3390/v15102131