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Immunogenicity and Tolerability of a SARS-CoV-2 TNX-1800, a Live Recombinant Poxvirus Vaccine Candidate, in Syrian Hamsters and New Zealand White Rabbits
TNX-1800 is a preclinical stage synthetic-derived live attenuated chimeric horsepox virus vaccine engineered to express the SARS-CoV-2 spike (S) gene. The objectives of this study were to assess the safety, tolerability, and immunogenicity of TNX-1800 administration in Syrian golden hamsters and New...
Autores principales: | Awasthi, Mayanka, Macaluso, Anthony, Goebel, Scott J., Luea, Erin, Noyce, Ryan S., Nasar, Farooq, Daugherty, Bruce, Bavari, Sina, Lederman, Seth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612059/ https://www.ncbi.nlm.nih.gov/pubmed/37896908 http://dx.doi.org/10.3390/v15102131 |
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