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Spatiotemporal evolution of AML immune microenvironment remodeling and RNF149-driven drug resistance through single-cell multidimensional analysis

BACKGROUND: The composition of the bone marrow immune microenvironment in patients with acute myeloid leukaemia (AML) was analysed by single-cell sequencing and the evolutionary role of different subpopulations of T cells in the development of AML and in driving drug resistance was explored in conju...

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Detalles Bibliográficos
Autores principales: Wu, Xin, Wu, Zhongguang, Deng, Woding, Xu, Rong, Ban, Chunmei, Sun, Xiaoying, Zhao, Qiangqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612211/
https://www.ncbi.nlm.nih.gov/pubmed/37891580
http://dx.doi.org/10.1186/s12967-023-04579-5