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Systems biology of industrial oxytetracycline production in Streptomyces rimosus: the secrets of a mutagenized hyperproducer

BACKGROUND: Oxytetracycline which is derived from Streptomyces rimosus, inhibits a wide range of bacteria and is industrially important. The underlying biosynthetic processes are complex and hinder rational engineering, so industrial manufacturing currently relies on classical mutants for production...

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Detalles Bibliográficos
Autores principales:	Beganovic, Selma, Rückert-Reed, Christian, Sucipto, Hilda, Shu, Wei, Gläser, Lars, Patschkowski, Thomas, Struck, Ben, Kalinowski, Jörn, Luzhetskyy, Andriy, Wittmann, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612213/ https://www.ncbi.nlm.nih.gov/pubmed/37898787 http://dx.doi.org/10.1186/s12934-023-02215-x

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