TMEM147 aggravates the progression of HCC by modulating cholesterol homeostasis, suppressing ferroptosis, and promoting the M2 polarization of tumor-associated macrophages

BACKGROUND: The endoplasmic reticulum (ER) regulates critical processes, including lipid synthesis, which are affected by transmembrane proteins localized in the ER membrane. One such protein, transmembrane protein 147 (TMEM147), has recently been implicated for its role in hepatocellular carcinoma...

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Detalles Bibliográficos
Autores principales: Huang, Jingjing, Pan, Huayang, Sun, Jing, Wu, Jiaming, Xuan, Qiyue, Wang, Jinge, Ke, Shanjia, Lu, Shounan, Li, Zihao, Feng, Zhigang, Hua, Yongliang, Yu, Qingan, Yin, Bing, Qian, Baolin, Zhou, Menghua, Xu, Yanan, Bai, Miaoyu, Zhang, Yingmei, Wu, Yaohua, Ma, Yong, Jiang, Hongchi, Dai, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612308/
https://www.ncbi.nlm.nih.gov/pubmed/37891677
http://dx.doi.org/10.1186/s13046-023-02865-0

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