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Sulindac sulfide as a non-immune suppressive γ-secretase modulator to target triple-negative breast cancer

INTRODUCTION: Triple-negative breast cancer (TNBC) comprises a heterogeneous group of clinically aggressive tumors with high risk of recurrence and metastasis. Current pharmacological treatment options remain largely limited to chemotherapy. Despite promising results, the efficacy of immunotherapy a...

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Detalles Bibliográficos
Autores principales: Hossain, Fokhrul, Ucar, Deniz A., Monticone, Giulia, Ran, Yong, Majumder, Samarpan, Larter, Kristina, Luu, Hanh, Wyczechowska, Dorota, Heidari, Soroor, Xu, Keli, Shanthalingam, Sudarvili, Matossian, Margarite, Xi, Yaguang, Burow, Matthew, Collins-Burow, Bridgette, Del Valle, Luis, Hicks, Chindo, Zabaleta, Jovanny, Golde, Todd, Osborne, Barbara, Miele, Lucio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612326/
https://www.ncbi.nlm.nih.gov/pubmed/37901240
http://dx.doi.org/10.3389/fimmu.2023.1244159