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The Relationship Between Myocardial Infarction and Estrogen Use: A Literature Review

This thorough literature evaluation was prompted by significant research into the complex interactions between estrogen use and myocardial infarction (MI). Estrogen has fascinated researchers because of its possible cardioprotective benefits and its impact on cardiovascular health. In order to clari...

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Autores principales: Javed, Ayesha, Ravi, Phanish C, Bilal Delvi, Sarah, Faraz Hussain, Iqra, Acosta G., Arnaldo J, Iqbal, Warda, Krishnamaneni, Vamsi, Alasaadi, Saya, Pradhan, Swetapadma, Vashisht, Rishabh, Modi, Shivani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612533/
https://www.ncbi.nlm.nih.gov/pubmed/37900417
http://dx.doi.org/10.7759/cureus.46134
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author Javed, Ayesha
Ravi, Phanish C
Bilal Delvi, Sarah
Faraz Hussain, Iqra
Acosta G., Arnaldo J
Iqbal, Warda
Krishnamaneni, Vamsi
Alasaadi, Saya
Pradhan, Swetapadma
Vashisht, Rishabh
Modi, Shivani
author_facet Javed, Ayesha
Ravi, Phanish C
Bilal Delvi, Sarah
Faraz Hussain, Iqra
Acosta G., Arnaldo J
Iqbal, Warda
Krishnamaneni, Vamsi
Alasaadi, Saya
Pradhan, Swetapadma
Vashisht, Rishabh
Modi, Shivani
author_sort Javed, Ayesha
collection PubMed
description This thorough literature evaluation was prompted by significant research into the complex interactions between estrogen use and myocardial infarction (MI). Estrogen has fascinated researchers because of its possible cardioprotective benefits and its impact on cardiovascular health. In order to clarify the connection between estrogen use and the risk of MI, this review critically examines the body of prior evidence. This review focuses on estrogen and its pivotal role in cardiovascular health, concentrating on lipid metabolism, vasodilation, inflammation, and endothelial function. It examines contentious data about estrogen therapy's heart-protective effects, taking into account age, initiation timing, dosage, and dosage of administration. Genetic and epigenetic influences on MI risk among estrogen users highlight intricate, personalized estrogen effects. The conclusion summarizes the main findings and emphasizes the need for an all-encompassing strategy for initiating and managing estrogen medication. It is crucial to consider patient-specific traits and risk factors to successfully customize treatment regimens. This review sheds vital light on the potential directions for better cardiovascular treatment for postmenopausal women by shedding light on the complex link between estrogen use and myocardial infarction. The review also identifies research gaps and future objectives in this area, highlighting the demand for novel medicines and individualized strategies to improve cardiovascular outcomes.
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spelling pubmed-106125332023-10-29 The Relationship Between Myocardial Infarction and Estrogen Use: A Literature Review Javed, Ayesha Ravi, Phanish C Bilal Delvi, Sarah Faraz Hussain, Iqra Acosta G., Arnaldo J Iqbal, Warda Krishnamaneni, Vamsi Alasaadi, Saya Pradhan, Swetapadma Vashisht, Rishabh Modi, Shivani Cureus Other This thorough literature evaluation was prompted by significant research into the complex interactions between estrogen use and myocardial infarction (MI). Estrogen has fascinated researchers because of its possible cardioprotective benefits and its impact on cardiovascular health. In order to clarify the connection between estrogen use and the risk of MI, this review critically examines the body of prior evidence. This review focuses on estrogen and its pivotal role in cardiovascular health, concentrating on lipid metabolism, vasodilation, inflammation, and endothelial function. It examines contentious data about estrogen therapy's heart-protective effects, taking into account age, initiation timing, dosage, and dosage of administration. Genetic and epigenetic influences on MI risk among estrogen users highlight intricate, personalized estrogen effects. The conclusion summarizes the main findings and emphasizes the need for an all-encompassing strategy for initiating and managing estrogen medication. It is crucial to consider patient-specific traits and risk factors to successfully customize treatment regimens. This review sheds vital light on the potential directions for better cardiovascular treatment for postmenopausal women by shedding light on the complex link between estrogen use and myocardial infarction. The review also identifies research gaps and future objectives in this area, highlighting the demand for novel medicines and individualized strategies to improve cardiovascular outcomes. Cureus 2023-09-28 /pmc/articles/PMC10612533/ /pubmed/37900417 http://dx.doi.org/10.7759/cureus.46134 Text en Copyright © 2023, Javed et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Other
Javed, Ayesha
Ravi, Phanish C
Bilal Delvi, Sarah
Faraz Hussain, Iqra
Acosta G., Arnaldo J
Iqbal, Warda
Krishnamaneni, Vamsi
Alasaadi, Saya
Pradhan, Swetapadma
Vashisht, Rishabh
Modi, Shivani
The Relationship Between Myocardial Infarction and Estrogen Use: A Literature Review
title The Relationship Between Myocardial Infarction and Estrogen Use: A Literature Review
title_full The Relationship Between Myocardial Infarction and Estrogen Use: A Literature Review
title_fullStr The Relationship Between Myocardial Infarction and Estrogen Use: A Literature Review
title_full_unstemmed The Relationship Between Myocardial Infarction and Estrogen Use: A Literature Review
title_short The Relationship Between Myocardial Infarction and Estrogen Use: A Literature Review
title_sort relationship between myocardial infarction and estrogen use: a literature review
topic Other
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612533/
https://www.ncbi.nlm.nih.gov/pubmed/37900417
http://dx.doi.org/10.7759/cureus.46134
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