Structural titration reveals Ca(2+)-dependent conformational landscape of the IP(3) receptor

Inositol 1,4,5-trisphosphate receptors (IP(3)Rs) are endoplasmic reticulum Ca(2+) channels whose biphasic dependence on cytosolic Ca(2+) gives rise to Ca(2+) oscillations that regulate fertilization, cell division and cell death. Despite the critical roles of IP(3)R-mediated Ca(2+) responses, the st...

Descripción completa

Detalles Bibliográficos
Autores principales: Paknejad, Navid, Sapuru, Vinay, Hite, Richard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613215/
https://www.ncbi.nlm.nih.gov/pubmed/37898605
http://dx.doi.org/10.1038/s41467-023-42707-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613215/
https://www.ncbi.nlm.nih.gov/pubmed/37898605
http://dx.doi.org/10.1038/s41467-023-42707-3

Ejemplares similares