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Structural titration reveals Ca(2+)-dependent conformational landscape of the IP(3) receptor
Inositol 1,4,5-trisphosphate receptors (IP(3)Rs) are endoplasmic reticulum Ca(2+) channels whose biphasic dependence on cytosolic Ca(2+) gives rise to Ca(2+) oscillations that regulate fertilization, cell division and cell death. Despite the critical roles of IP(3)R-mediated Ca(2+) responses, the st...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613215/ https://www.ncbi.nlm.nih.gov/pubmed/37898605 http://dx.doi.org/10.1038/s41467-023-42707-3 |