A phosphoinositide switch mediates exocyst recruitment to multivesicular endosomes for exosome secretion

Exosomes are secreted to the extracellular milieu when multivesicular endosomes (MVEs) dock and fuse with the plasma membrane. However, MVEs are also known to fuse with lysosomes for degradation. How MVEs are directed to the plasma membrane for exosome secretion rather than to lysosomes is unclear....

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Detalles Bibliográficos
Autores principales: Liu, Di-Ao, Tao, Kai, Wu, Bin, Yu, Ziyan, Szczepaniak, Malwina, Rames, Matthew, Yang, Changsong, Svitkina, Tatyana, Zhu, Yueyao, Xu, Fengyuan, Nan, Xiaolin, Guo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613218/
https://www.ncbi.nlm.nih.gov/pubmed/37898620
http://dx.doi.org/10.1038/s41467-023-42661-0

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