Long-term viable chimeric nephrons generated from progenitor cells are a reliable model in cisplatin-induced toxicity

Kidney organoids have shown promise as evaluation tools, but their in vitro maturity remains limited. Transplantation into adult mice has aided in maturation; however, their lack of urinary tract connection limits long-term viability. Thus, long-term viable generated nephrons have not been demonstra...

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Detalles Bibliográficos
Autores principales: Matsui, Kenji, Yamanaka, Shuichiro, Chen, Sandy, Matsumoto, Naoto, Morimoto, Keita, Kinoshita, Yoshitaka, Inage, Yuka, Saito, Yatsumu, Takamura, Tsuyoshi, Fujimoto, Toshinari, Tajiri, Susumu, Matsumoto, Kei, Kobayashi, Eiji, Yokoo, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613230/
https://www.ncbi.nlm.nih.gov/pubmed/37898693
http://dx.doi.org/10.1038/s42003-023-05484-9

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