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Tracing multiple scattering trajectories for deep optical imaging in scattering media

Multiple light scattering hampers imaging objects in complex scattering media. Approaches used in real practices mainly aim to filter out multiple scattering obscuring the ballistic waves that travel straight through the scattering medium. Here, we propose a method that makes the deterministic use o...

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Autores principales: Kang, Sungsam, Kwon, Yongwoo, Lee, Hojun, Kim, Seho, Hong, Jin Hee, Yoon, Seokchan, Choi, Wonshik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613237/
https://www.ncbi.nlm.nih.gov/pubmed/37898596
http://dx.doi.org/10.1038/s41467-023-42525-7
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author Kang, Sungsam
Kwon, Yongwoo
Lee, Hojun
Kim, Seho
Hong, Jin Hee
Yoon, Seokchan
Choi, Wonshik
author_facet Kang, Sungsam
Kwon, Yongwoo
Lee, Hojun
Kim, Seho
Hong, Jin Hee
Yoon, Seokchan
Choi, Wonshik
author_sort Kang, Sungsam
collection PubMed
description Multiple light scattering hampers imaging objects in complex scattering media. Approaches used in real practices mainly aim to filter out multiple scattering obscuring the ballistic waves that travel straight through the scattering medium. Here, we propose a method that makes the deterministic use of multiple scattering for microscopic imaging of an object embedded deep within scattering media. The proposed method finds a stack of multiple complex phase plates that generate similar light trajectories as the original scattering medium. By implementing the inverse scattering using the identified phase plates, our method rectifies multiple scattering and amplifies ballistic waves by almost 600 times. This leads to a significant increase in imaging depth—more than three times the scattering mean free path—as well as the correction of image distortions. Our study marks an important milestone in solving the long-standing high-order inverse scattering problems.
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spelling pubmed-106132372023-10-30 Tracing multiple scattering trajectories for deep optical imaging in scattering media Kang, Sungsam Kwon, Yongwoo Lee, Hojun Kim, Seho Hong, Jin Hee Yoon, Seokchan Choi, Wonshik Nat Commun Article Multiple light scattering hampers imaging objects in complex scattering media. Approaches used in real practices mainly aim to filter out multiple scattering obscuring the ballistic waves that travel straight through the scattering medium. Here, we propose a method that makes the deterministic use of multiple scattering for microscopic imaging of an object embedded deep within scattering media. The proposed method finds a stack of multiple complex phase plates that generate similar light trajectories as the original scattering medium. By implementing the inverse scattering using the identified phase plates, our method rectifies multiple scattering and amplifies ballistic waves by almost 600 times. This leads to a significant increase in imaging depth—more than three times the scattering mean free path—as well as the correction of image distortions. Our study marks an important milestone in solving the long-standing high-order inverse scattering problems. Nature Publishing Group UK 2023-10-28 /pmc/articles/PMC10613237/ /pubmed/37898596 http://dx.doi.org/10.1038/s41467-023-42525-7 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Kang, Sungsam
Kwon, Yongwoo
Lee, Hojun
Kim, Seho
Hong, Jin Hee
Yoon, Seokchan
Choi, Wonshik
Tracing multiple scattering trajectories for deep optical imaging in scattering media
title Tracing multiple scattering trajectories for deep optical imaging in scattering media
title_full Tracing multiple scattering trajectories for deep optical imaging in scattering media
title_fullStr Tracing multiple scattering trajectories for deep optical imaging in scattering media
title_full_unstemmed Tracing multiple scattering trajectories for deep optical imaging in scattering media
title_short Tracing multiple scattering trajectories for deep optical imaging in scattering media
title_sort tracing multiple scattering trajectories for deep optical imaging in scattering media
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613237/
https://www.ncbi.nlm.nih.gov/pubmed/37898596
http://dx.doi.org/10.1038/s41467-023-42525-7
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