Cargando…
Tracing multiple scattering trajectories for deep optical imaging in scattering media
Multiple light scattering hampers imaging objects in complex scattering media. Approaches used in real practices mainly aim to filter out multiple scattering obscuring the ballistic waves that travel straight through the scattering medium. Here, we propose a method that makes the deterministic use o...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613237/ https://www.ncbi.nlm.nih.gov/pubmed/37898596 http://dx.doi.org/10.1038/s41467-023-42525-7 |
_version_ | 1785128787057311744 |
---|---|
author | Kang, Sungsam Kwon, Yongwoo Lee, Hojun Kim, Seho Hong, Jin Hee Yoon, Seokchan Choi, Wonshik |
author_facet | Kang, Sungsam Kwon, Yongwoo Lee, Hojun Kim, Seho Hong, Jin Hee Yoon, Seokchan Choi, Wonshik |
author_sort | Kang, Sungsam |
collection | PubMed |
description | Multiple light scattering hampers imaging objects in complex scattering media. Approaches used in real practices mainly aim to filter out multiple scattering obscuring the ballistic waves that travel straight through the scattering medium. Here, we propose a method that makes the deterministic use of multiple scattering for microscopic imaging of an object embedded deep within scattering media. The proposed method finds a stack of multiple complex phase plates that generate similar light trajectories as the original scattering medium. By implementing the inverse scattering using the identified phase plates, our method rectifies multiple scattering and amplifies ballistic waves by almost 600 times. This leads to a significant increase in imaging depth—more than three times the scattering mean free path—as well as the correction of image distortions. Our study marks an important milestone in solving the long-standing high-order inverse scattering problems. |
format | Online Article Text |
id | pubmed-10613237 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-106132372023-10-30 Tracing multiple scattering trajectories for deep optical imaging in scattering media Kang, Sungsam Kwon, Yongwoo Lee, Hojun Kim, Seho Hong, Jin Hee Yoon, Seokchan Choi, Wonshik Nat Commun Article Multiple light scattering hampers imaging objects in complex scattering media. Approaches used in real practices mainly aim to filter out multiple scattering obscuring the ballistic waves that travel straight through the scattering medium. Here, we propose a method that makes the deterministic use of multiple scattering for microscopic imaging of an object embedded deep within scattering media. The proposed method finds a stack of multiple complex phase plates that generate similar light trajectories as the original scattering medium. By implementing the inverse scattering using the identified phase plates, our method rectifies multiple scattering and amplifies ballistic waves by almost 600 times. This leads to a significant increase in imaging depth—more than three times the scattering mean free path—as well as the correction of image distortions. Our study marks an important milestone in solving the long-standing high-order inverse scattering problems. Nature Publishing Group UK 2023-10-28 /pmc/articles/PMC10613237/ /pubmed/37898596 http://dx.doi.org/10.1038/s41467-023-42525-7 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Kang, Sungsam Kwon, Yongwoo Lee, Hojun Kim, Seho Hong, Jin Hee Yoon, Seokchan Choi, Wonshik Tracing multiple scattering trajectories for deep optical imaging in scattering media |
title | Tracing multiple scattering trajectories for deep optical imaging in scattering media |
title_full | Tracing multiple scattering trajectories for deep optical imaging in scattering media |
title_fullStr | Tracing multiple scattering trajectories for deep optical imaging in scattering media |
title_full_unstemmed | Tracing multiple scattering trajectories for deep optical imaging in scattering media |
title_short | Tracing multiple scattering trajectories for deep optical imaging in scattering media |
title_sort | tracing multiple scattering trajectories for deep optical imaging in scattering media |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613237/ https://www.ncbi.nlm.nih.gov/pubmed/37898596 http://dx.doi.org/10.1038/s41467-023-42525-7 |
work_keys_str_mv | AT kangsungsam tracingmultiplescatteringtrajectoriesfordeepopticalimaginginscatteringmedia AT kwonyongwoo tracingmultiplescatteringtrajectoriesfordeepopticalimaginginscatteringmedia AT leehojun tracingmultiplescatteringtrajectoriesfordeepopticalimaginginscatteringmedia AT kimseho tracingmultiplescatteringtrajectoriesfordeepopticalimaginginscatteringmedia AT hongjinhee tracingmultiplescatteringtrajectoriesfordeepopticalimaginginscatteringmedia AT yoonseokchan tracingmultiplescatteringtrajectoriesfordeepopticalimaginginscatteringmedia AT choiwonshik tracingmultiplescatteringtrajectoriesfordeepopticalimaginginscatteringmedia |