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CYP1A2 expression rather than genotype is associated with olanzapine concentration in psychiatric patients

Olanzapine is a commonly prescribed atypical antipsychotic agent for treatment of patients with schizophrenia and bipolar disorders. Previous in vitro studies using human liver microsomes identified CYP1A2 and CYP2D6 enzymes being responsible for CYP-mediated metabolism of olanzapine. The present wo...

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Detalles Bibliográficos
Autores principales:	Fekete, Ferenc, Menus, Ádám, Tóth, Katalin, Kiss, Ádám Ferenc, Minus, Annamária, Sirok, Dávid, Belič, Aleš, Póti, Ádám, Csukly, Gábor, Monostory, Katalin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613299/ https://www.ncbi.nlm.nih.gov/pubmed/37898643 http://dx.doi.org/10.1038/s41598-023-45752-6

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