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Neuroprotective Effects of Leptin on the APP/PS1 Alzheimer’s Disease Mouse Model: Role of Microglial and Neuroinflammation

BACKGROUND: Microglia are closely linked to Alzheimer’s disease (AD) many years ago; however, the pathological mechanisms of AD remain unclear. The purpose of this study was to determine whether leptin affected microglia in the hippocampus of young and aged male APP/PS1 mice. OBJECTIVE: In a transge...

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Detalles Bibliográficos
Autores principales:	Ma, Jing, Hou, Yi-Hui, Liao, Zhe-Yan, Ma, Zheng, Zhang, Xiao-Xuan, Wang, Jian-Li, Zhu, Yun-Bo, Shan, Hai-Lei, Wang, Ping-Yue, Li, Cheng-Bo, Lv, Ying-Lei, Wei, Yi-Lan, Dou, Jie-Zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613410/ https://www.ncbi.nlm.nih.gov/pubmed/37905186 http://dx.doi.org/10.2147/DNND.S427781

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