Heterogeneous off-target impact of ion-channel deletion on intrinsic properties of hippocampal model neurons that self-regulate calcium

How do neurons that implement cell-autonomous self-regulation of calcium react to knockout of individual ion-channel conductances? To address this question, we used a heterogeneous population of 78 conductance-based models of hippocampal pyramidal neurons that maintained cell-autonomous calcium home...

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Detalles Bibliográficos
Autores principales: Srikanth, Sunandha, Narayanan, Rishikesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613471/
https://www.ncbi.nlm.nih.gov/pubmed/37904732
http://dx.doi.org/10.3389/fncel.2023.1241450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613471/
https://www.ncbi.nlm.nih.gov/pubmed/37904732
http://dx.doi.org/10.3389/fncel.2023.1241450

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