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Cutaneous Metastases in Progressive Prostate Adenocarcinoma: A Case Report and Literature Review

Prostate cancer has an indolent progression course and commonly metastasizes to the vertebrae bone and regional lymph nodes. We report a patient with prostate cancer who has developed cutaneous metastases in multiple regions, including the right infraclavicular and abdominal area, as well as the lef...

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Autores principales: Brito, Yesenia, Wilson, Bruce W, Bacchus, Kavonne I, Mwaniki, Janice, Jorge, Juaquito, Tiesenga, Frederick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613505/
https://www.ncbi.nlm.nih.gov/pubmed/37905289
http://dx.doi.org/10.7759/cureus.46219
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author Brito, Yesenia
Wilson, Bruce W
Bacchus, Kavonne I
Mwaniki, Janice
Jorge, Juaquito
Tiesenga, Frederick
author_facet Brito, Yesenia
Wilson, Bruce W
Bacchus, Kavonne I
Mwaniki, Janice
Jorge, Juaquito
Tiesenga, Frederick
author_sort Brito, Yesenia
collection PubMed
description Prostate cancer has an indolent progression course and commonly metastasizes to the vertebrae bone and regional lymph nodes. We report a patient with prostate cancer who has developed cutaneous metastases in multiple regions, including the right infraclavicular and abdominal area, as well as the left supraclavicular region. It presented as isolated, prominent nodules that were microscopically proven to be of prostate adenocarcinoma when biopsied. This rare presentation is a marker of an advanced disease course with a poor prognosis in castrate-resistant prostate cancer. Thorough clinical examination to rule out metastasis from the prostate and other dermatological conditions is paramount as well as ensuring early detection and optimizing patient outcomes.
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spelling pubmed-106135052023-10-30 Cutaneous Metastases in Progressive Prostate Adenocarcinoma: A Case Report and Literature Review Brito, Yesenia Wilson, Bruce W Bacchus, Kavonne I Mwaniki, Janice Jorge, Juaquito Tiesenga, Frederick Cureus Pathology Prostate cancer has an indolent progression course and commonly metastasizes to the vertebrae bone and regional lymph nodes. We report a patient with prostate cancer who has developed cutaneous metastases in multiple regions, including the right infraclavicular and abdominal area, as well as the left supraclavicular region. It presented as isolated, prominent nodules that were microscopically proven to be of prostate adenocarcinoma when biopsied. This rare presentation is a marker of an advanced disease course with a poor prognosis in castrate-resistant prostate cancer. Thorough clinical examination to rule out metastasis from the prostate and other dermatological conditions is paramount as well as ensuring early detection and optimizing patient outcomes. Cureus 2023-09-29 /pmc/articles/PMC10613505/ /pubmed/37905289 http://dx.doi.org/10.7759/cureus.46219 Text en Copyright © 2023, Brito et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Brito, Yesenia
Wilson, Bruce W
Bacchus, Kavonne I
Mwaniki, Janice
Jorge, Juaquito
Tiesenga, Frederick
Cutaneous Metastases in Progressive Prostate Adenocarcinoma: A Case Report and Literature Review
title Cutaneous Metastases in Progressive Prostate Adenocarcinoma: A Case Report and Literature Review
title_full Cutaneous Metastases in Progressive Prostate Adenocarcinoma: A Case Report and Literature Review
title_fullStr Cutaneous Metastases in Progressive Prostate Adenocarcinoma: A Case Report and Literature Review
title_full_unstemmed Cutaneous Metastases in Progressive Prostate Adenocarcinoma: A Case Report and Literature Review
title_short Cutaneous Metastases in Progressive Prostate Adenocarcinoma: A Case Report and Literature Review
title_sort cutaneous metastases in progressive prostate adenocarcinoma: a case report and literature review
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613505/
https://www.ncbi.nlm.nih.gov/pubmed/37905289
http://dx.doi.org/10.7759/cureus.46219
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