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Dexmedetomidine Ameliorates Cardiac Ischemia/Reperfusion Injury by Enhancing Autophagy Through Activation of the AMPK/SIRT3 Pathway

OBJECTIVE: Myocardial ischemia-reperfusion (I/R) injury is a detrimental disease, resulting in high morbidity and mortality globally. In this study, we aimed to investigate the role of Dex in mitigating cardiac I/R injury. METHODS: H9c2 cells were treated with Dex (1 μM) for 24 h followed by oxygen-...

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Detalles Bibliográficos
Autores principales: He, Hong, Liu, Peng, Li, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10613569/
https://www.ncbi.nlm.nih.gov/pubmed/37908314
http://dx.doi.org/10.2147/DDDT.S428024